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临床试验/NCT07669792
NCT07669792招募中不适用

Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis): A Randomized Clinical Trial

British University In Egypt1 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2025年6月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
16
试验地点
1

研究概览

简要总结

The purpose of the study is the comparison of bone gained histologically from the Bone Shell Khoury's Technique in comparison with the usage of non-resorbable membrane polytetrafluoroethylene and discussing its eligibility for implant placement in restoring the atrophic posterior mandible.

详细描述

The aim of this study is to assess the bone gained histologically when comparing the following different techniques:

One of the techniques that is used for bone augmentation is the Khoury technique which entails that a split cortical bone shell obtained from the ramus area through piezoelectric surgery. The thin laminae of bone obtained is stabilized in the defect area labially through micro screws and the generated gap is filled through a mixture of autogenous that could be obtained from the retromolar area through special burs as the auto chip maker (ACM) or via bone scrapper. The obtained is mixed with an equal ratio with xenograft or bone obtained from animal source to fill the created gap.

Another technique involves the usage of a non-resorbable membrane known as reinforced titanium PTFE that is stabilized from both the lingual and labial aspects via micro screws .It's then filled with a mixture of both autogenous and xenograft for maximizing the bone formation capability. In some cases, the reinforced titanium PTFE is covered with collagen membrane to avoid one of the common drawbacks of this technique which is wound dehiscence.

This study aims to evaluate the bone quality gained from both techniques.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Have two or more missing teeth in the posterior mandibular segment.
  • The patients age of 18 and above.
  • The alveolar ridge in the edentulous site of the selected patients will have a buccolingual width of less than 4mm.
  • Sufficient vertical bone height.
  • Free of any local or systemic condition that may contraindicate ridge expansion procedure.

排除标准

  • Patients taking any medication that may interfere with bone healing or bone biology.
  • Patients with any systemic disease that may affect bone healing.
  • Any patients with any previous bone grafting procedure at the site of interest.
  • Patient's that have been diagnosed with periodontal disease, as sufficient ridge height would be improbable.
  • Patients with significant vitamin D deficiency.

研究组 & 干预措施

Bone Shell Khoury's Technique

Active Comparator

This group will receive a block graft using Khoury Technique.

干预措施: Bone Shell Khoury's Technique (Procedure)

GBR using Ti based PTFE

Experimental

This group will receive a non resorbable membrane using titanium reinforced polytetrafluorethylene membrane.

干预措施: GBR using Ti based PTFE (Procedure)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Abdelaziz

Master's Candidate

British University In Egypt

研究点 (1)

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