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se of Clevira in COVID19 patients

Phase 3
Completed
Conditions
Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Registration Number
CTRI/2020/05/025483
Lead Sponsor
Apex Laboratories Pvt Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

1. Willing and able to provide written informed consent prior to performing study procedures.

2. Males and females between the age of 18-50 years.

3. Mild to moderate COVID-19 associated disease as defined by the WHO.

4. Hospitalized patient.

5. Has laboratory-confirmed SARS-CoV-2 infection as determined by RT-PCR.

6.Illness of any duration and febrile/afebrile. Febrile-defined as temperature >= 36.6 °C armpit, >= 37.2 °C oral, or >= 37.8 °C rectal documented within 48 hours of consent.

Exclusion Criteria

1. Participation in any other clinical trial of an experimental treatment for COVID-19

2.Concurrent treatment with other agents with actual or possible direct acting antiviral activity against SARS-CoV-2 is prohibited < 24 hours prior to study medication initiation

3.Alanine Aminotransferase (ALT) or aspartate aminotransferase (AST) > 5 X upper limit of normal (ULN)

4.Stage 4 severe chronic kidney disease or requiring dialysis (i.e. eGFR < 30)

5.Pregnant women or women who are breastfeeding

6.Immunocompromised patients taking medication upon screening

7.Consideration by the investigator, for any reason, that the subject is an unsuitable candidate to receive study treatment

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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