Effect of Vitamin E on Dry eye
Phase 3
Recruiting
- Conditions
- Dry eye.
- Registration Number
- IRCT20190929044926N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Patients with Dry eye syndrome and questionnaire score above 10
TBUT test below 10 sec.
SM Tube test below 5 mm.
Age range of 18-60 years
Ability and consent of the patients to take part in the study
Non pregnant female participants
No allergic or reaction history of taking vitamin E
No history of blood coagulation disease
No history of taking vitamin E supplement over the past 3 months
Exclusion Criteria
Patients with allergic or any kind of reactions with taking vitamin E
Patients with blood disorders/coagulation problems
Surgery history of Refractive errors
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of tear secretion. Timepoint: Evaluating the amount of tear secretion in the beginning of the study and two weeks after the intervention is done. Method of measurement: Evaluating with Strip Meniscometry Test (SMTube).;Tear Break Up Time. Timepoint: Evaluating the Tear Break Up Time in the beginning of the study and two weeks after the intervention is done. Method of measurement: Evaluating with TBUT (Tear Break Up Time) test.;Symptoms of Dry eye. Timepoint: Evaluating the symptoms of Dry eye in the beginning of the study and two weeks after the intervention is done. Method of measurement: Evaluating with Ocular Surface Disease Index questionnaire.
- Secondary Outcome Measures
Name Time Method