Observatoire Brestois Des Néoplasies Myéloprolifératives
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Overall Survival
研究概览
简要总结
All patients diagnosed or followed in Brest University Hospital for Philadelphia negative myeloproliferative neoplasms will be included in this observational study.
Myeloproliferative neoplasms recorded included: polycythemia vera, essential Thrombocythemia and Primary Myelofibrosis.
This is a not interventional study. Alive patients need to sign a non-opposition consent form.
Patients will be followed until last news (death, change of reference centre...).
详细描述
In this retrospective and prospective study, clinical and biological data from diagnosis until last news will be recorded.
Clinical data collected: patients and disease characteristics at the time of the diagnosis, disease and mutational status, cardio-vascular risk factors, history of thrombosis and cancer.
Biological data collected: hemogram and bone marrow results if available. During the follow-up new data will be noted: treatment changes (reasons of change and type of drug), thrombotic events (localization, date and hemogram), phenotypic evolutions (type and date), death (date and etiology).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with essentiel thrombocythemia, polycythemia vera or primary myelofibrosis
- •Signature of the non-opposition consent form
排除标准
- 未提供
结局指标
主要结局
Overall Survival
时间窗: 10 years
occurrence of death
次要结局
- Incidence of evolutions(10 years)
- Incidence of thromboses(10 years)