Does ischaemic pre-conditioning reduce renal damage during elective infra-renal aortic aneurysm repair? Randomised controlled trial.

Completed

• Conditions: Abdominal aortic aneurysm; Circulatory System; Aortic aneurysm

• Registration Number: ISRCTN89918035
• Lead Sponsor: Cambridge University Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-11-15
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients undergoing elective open repair of an infra-renal abdominal aortic aneurysm.

Exclusion Criteria

1. Pre-existing renal failure
2. Baseline serum creatinine >150 µmols/l
3. Baseline serum urea >20 mmols/l
4. Previous history of acute renal failure
5. Previous renal transplant
6. Previous renal disease
7. Previous endovascular aneurysm repair
8. Previous renal replacement therapy
9. Suprarenal aneurysm
10. Ankle-brachial pressure index <0.7

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Post-operative urinary albumin-creatinine ratios<br>2. Post-operative creatinine clearance<br>3. Post-operative glomerular filtration rate

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures