Effect of Stent Placement on Short Term Survival of Left Sided Obstructive Colorectal Cancers. Comparison of Bridge-To-Surgery Versus Emergency Surgery Approaches
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 65
- 主要终点
- Disease Free Survival
研究概览
简要总结
The aim of this observational study is to determine effect of stent placement on survival results in first three years in a patient who applied to the emergency department with obstruction due to colorectal cancer. Eligible patients divided into two groups. Group A includes patients underwent emergency surgery directly. Patients underwent elective surgery following stent placement as bridge-to-surgery. Patients underwent elective surgery following bridge-to-surgery stent placement were accepted as Group B.
详细描述
Patients who applied to emergency department of a single tertiary referral center between January 2016 and December 2020 and diagnosed as left sided obstructive colorectal cancer were included in this retrospective study. All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms.
Patients were excluded from the analysis if they met any of the following criteria:
- Who underwent emergency surgery due to unsuccessful stent application intervention or stent-related complications developed,
- Those with middle and lower rectum tumors or received neoadjuvant treatment,
- Perforation,
- Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.),
- Recurrent disease patients
- Patients have metastasis
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms and diagnosed as left sided (descending colon, sigmoid colon and upper rectum) obstructive colorectal cancer were included
排除标准
- •Who underwent emergency surgery due to unsuccessful stent placement intervention
- •Who underwent emergency surgery due to stent-related complications
- •Those with middle and lower rectum tumors
- •Those received neoadjuvant treatment,
- •Patients have perforation,
- •Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.),
- •Who has a recurrent disease or metastasis.
结局指标
主要结局
Disease Free Survival
时间窗: 3 years
The local or systemic recurrence free time period of patient after being diagnosed as colorectal cancer after coming to emergency department
Overall Survival
时间窗: 3 years
The survival time of patient after being diagnosed as colorectal cancer after coming to emergency department
次要结局
- Serious complications(90 days)
- Minimally invasive surgery(90 days)
- End colostomy rate(90 days)
- Mortality(90 days)
研究者
Yasir Musa Kesgin, MD
MD
Kanuni Sultan Suleyman Training and Research Hospital