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临床试验/CTRI/2026/02/103456
CTRI/2026/02/103456尚未招募不适用

Clinical outcomes with levonorgestrel releasing intrauterine system versus laparoscopic hysterectomy in AUB

KASTURBA MEDICAL COLLEGE MANIPAL1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2026年2月16日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
88
试验地点
1

研究概览

简要总结

Abnormal uterine bleeding or AUB is a common condition that significantly affects women’s quality of life and is classified using the FIGO PALM COEIN system. Although hysterectomy has traditionally been the definitive treatment, it carries surgical and psychological risks. The levonorgestrel-releasing intrauterine system has emerged as an effective, conservative alternative that reduces menstrual blood loss, improves haemoglobin levels, and enhances quality of life. Multiple studies have shown high satisfaction rates and significant symptom improvement with LNG-IUS. Comparative research indicates that while hysterectomy offers higher satisfaction for some women, LNG-IUS is associated with fewer complications and is cost-effective. Indian studies similarly demonstrate the strong efficacy and acceptability of LNG-IUS. Despite growing evidence supporting both treatments, no standardised guideline exists to guide choice between LNG-IUS and hysterectomy, highlighting the need for further comparative studies to inform clinical decision-making and improve patient counselling.

研究设计

研究类型
Observational

入排标准

年龄范围
30.00 Year(s) 至 60.00 Year(s)(—)
性别
Female

入选标准

  • AUB-A (Adenomyosis),P (POLYP), AUB-L (Leiomyoma less than , equal to 16 weeks size).

排除标准

  • AUB-L (leiomyoma more than 16 weeks size), AUB-C (Coagulopathy), AUB-I (Iatrogenic), AUB-N (Neoplasia), AV malformations.

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Shambhavi Singh

Kasturba Medical College, Manipal

研究点 (1)

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