Effects of vaginal prolapse surgery on innervation of the vagina.
Recruiting
- Conditions
- Prolapse, Surgery, Innervation, Vagina
- Registration Number
- NL-OMON22450
- Lead Sponsor
- Academic Medical Centre (AMC)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
1. Patients undergoing primary prolapse surgery because of vaginal prolapse stage ≥ 2 in either the anterior or posterior compartment;
2. Sexually active women, sexually active meaning:
Exclusion Criteria
1. Previous pelvic surgery;
2. Previous pelvic irradiation;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effects of prolapse surgery on vaginal nerve density quantified in vaginal epithelial layer biopsies (diameter 4 mm) taken before surgery and at 6 weeks and 6 months after surgery.
- Secondary Outcome Measures
Name Time Method Pelvic floor function measured using the UDI-6, IIQ-7 and PISQ-12 questionnaires before and 6 months after surgery.