Comparison of Small Colorectal Polyp Removal Using Cold EMR With Hot EMR
- Conditions
- Colonic Polyps
- Registration Number
- NCT03000868
- Lead Sponsor
- Chonnam National University Hospital
- Brief Summary
This study evaluates the efficacy of small colorectal polyp removal using cold endoscopic mucosal resection with hot endoscopic mucosal resection. Half of the participants will receive cold endoscopic mucosal resection, while the other half will receive hot endoscopic mucosal resection.
- Detailed Description
Colorectal polyps are considered as precancerous lesions and endoscopical resection is currently the treatment of choice when it is possible.
Colorectal polyps are classified into diminutive polyps (\<5mm in diameter), small polyps (6-9mm in diameter), and large polyps (\>1cm in diameter). There are several endoscopical treatment methods: cold biopsy forceps polypectomy, cold snare polypectomy, hot biopsy forceps polypectomy, hot snare polypectomy, and endoscopic mucosal resection. Cold polypectomy means mechanical removal of the polyp with snare or biopsy forceps without the use of electrocautery, and hot polypectomy means removal of the polyp with the use of electocautery.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
-
Patients with colorectal polyps that are <1cm in diameter who need endoscopic mucosal resection.
- Patients who gave informed consents to this study.
- Patients under the age of 19
- Patients who are receiving antiplatelet or anticoagulant therapies
- Patients with hypercoagulability (i.e., liver cirrhosis, hemophilia, end-stage renal disease, or chronic kidney disease)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Complete removal of the colorectal polyp At the time of the procedure (endoscopic mucosal resection) The resected specimen will be reviewed microscopically to assess complete resection including the lateral and base margins
- Secondary Outcome Measures
Name Time Method Procedure time At the time of the procedure (endoscopic mucosal resection) The time needed for the hot EMR vs cold EMR (minutes) will be assessed.
Complication after endoscopic mucosal resection Within 1 month Procedure-related complications (bleeding, perforation, and post-coagulation syndrome) will be assessed.
Trial Locations
- Locations (1)
Chonnam National University Hospital
🇰🇷Gwangju, Korea, Republic of
Chonnam National University Hospital🇰🇷Gwangju, Korea, Republic of