Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Phase 2
Completed
- Conditions
- ATROPHIC ACNE SCARS
- Interventions
- Drug: PRP( platelet rich plasma) and Insulin human
- Registration Number
- NCT06002854
- Lead Sponsor
- Jinnah Postgraduate Medical Centre
- Brief Summary
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- postacne atrophic scars ≥ 2 on Goodman and Baron's acne scar-grading system
- Either gender.
- Age 20-50 years.
Exclusion Criteria
- lactation and pregnancy
- skin cancers and infection
- photosensitivity like SLE ,XP
- use of RETINOIDS in last 6 months.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description GROUP A Microneedling with PRP(platelete rich plasma) PRP( platelet rich plasma) and Insulin human - GROUP B Microneedling with topical INSULIN PRP( platelet rich plasma) and Insulin human -
- Primary Outcome Measures
Name Time Method Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars Efficacy will be assesed upto 4 months. Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
JPMC
🇵🇰Karachi, Sindh, Pakistan