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Clinical Trials/NCT06691438
NCT06691438
Not yet recruiting
Not Applicable

Evaluation of the Effect on Pain of Attentional Diversion Associated with Hypnotic Induction by Virtual Reality (VRH) in Perioperative Prostate Biopsies Under Local Anesthesia: Prospective Randomized and Controlled Trial

University Hospital, Grenoble1 site in 1 country130 target enrollmentDecember 1, 2024
ConditionsProstate Biopsy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prostate Biopsy
Sponsor
University Hospital, Grenoble
Enrollment
130
Locations
1
Primary Endpoint
To prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, transrectally or transperineally, under local anesthesia with or without a virtual reality hypnosis headset.
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

The primary objective of the study is to prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, either transrectally or transperineally, under local anesthesia with or without a virtual reality hypnosis headset. The study was sized based on a mean pain reduction of 1.5 points on a numerical scale (0-10 NAS), with an estimate of procedure-related pain of 4.0 on the NAS scale.

Detailed Description

Prospective comparison of pain during the procedure assessed in patients treated for prostate biopsies under local anesthesia with or without a virtual reality headset.No additional examination will be performed in addition to the conventional management of a biopsy except for the fitting of the headset for patients randomized to the "with virtual reality headset" group. Patients will be randomized on the same day of the procedure into one of the two study groups. A single follow-up visit will be performed postoperatively 1 month after surgery.

Registry
clinicaltrials.gov
Start Date
December 1, 2024
End Date
October 1, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Sponsor
University Hospital, Grenoble
Responsible Party
Principal Investigator
Principal Investigator

EssaiClinique_HYPNOSURG-VR

Professeur

University Hospital, Grenoble

Eligibility Criteria

Inclusion Criteria

  • Adult patients who are candidates for ultrasound-guided prostate biopsies under local anesthesia, via transperineal or transrectal route
  • Patient having signed informed consent

Exclusion Criteria

  • Patient suffering from blindness or any other visual handicap that contraindicates the use of the headset
  • Deaf or hard of hearing patients
  • Patients suffering from epilepsy and/or mental deficiency, and/or disorders of higher functions
  • Psychotic patients
  • Claustrophobic patients or those who cannot tolerate a mask over their eyes
  • Refusal of local anesthesia
  • Protected person (art. L1121-5 to L1121-8 of the CSP)

Outcomes

Primary Outcomes

To prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, transrectally or transperineally, under local anesthesia with or without a virtual reality hypnosis headset.

Time Frame: after the procedure

maximum pain felt during the procedure on a numerical EN scale, ranging from 0 (no pain) to 10 (extreme pain). The values will be collected directly at the end of the procedure.

Secondary Outcomes

  • Pain after the procedure(when leaving the hospital)
  • Stress during the procedure(after the procedure)
  • Immersion during hypnosis(at the procedure)
  • Evaluation of the nociceptive response to painful stimuli(during the procedure)
  • Satisfaction with the procedure(after the procedure)
  • Duration of the procedure(after the procedure)
  • Length of stay in hospital / outpatient care(at 1 month)
  • Success of biopsies(at 1 month)
  • Need for general anesthesia(after the procedure)
  • Pain upon returning home the same evening and on D1(after procedure, at 1 day after procedure)
  • Adverse effects related to the procedure during one month(at 1 month)
  • Qualitative assessment of the patient's experience(after the procedure)

Study Sites (1)

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