MedPath

A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis

Phase 4
Active, not recruiting
Conditions
Rheumatoid Arthritis
Interventions
Registration Number
NCT03915964
Lead Sponsor
Eli Lilly and Company
Brief Summary

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
2600
Inclusion Criteria
  • Participants must have at least one of the following characteristics:

    • Documented evidence of a VTE prior to this study
    • At least 60 years of age
    • A body mass index (BMI) greater than or equal to 30 kilograms per meter squared (kg/m²), or
    • Age 50 to less than 60 years and BMI 25 to less than 30 kg/m².
  • Participants must have an inadequate response or intolerance to at least 1 disease-modifying antirheumatic drugs (DMARD) (synthetic or biologic).

Read More
Exclusion Criteria
  • Participant should have no reason to not take a TNF inhibitor.
  • Participants must not be pregnant or breastfeeding.
  • Participants must not have had more than one VTE.
  • Participants must not have cancer.
  • Participants must not have active herpes zoster, serious infection, active tuberculosis, or any other serious illness.
  • Participants must not have had a live vaccine within four weeks of study start.
  • Participants must not have participated in any other clinical trial within four weeks of study start.
  • Participants must not have a history of IV drug use, other illicit drug abuse, or chronic alcohol abuse in the past year.
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
TNF InhibitorTNF InhibitorAdalimumab or etanercept administered subcutaneously (SC) per standard of care.
Baricitinib High DoseBaricitinibBaricitinib administered orally.
Baricitinib Low DoseBaricitinibBaricitinib administered orally.
Primary Outcome Measures
NameTimeMethod
Time from First Dose of Study Treatment to First Event of Venous Thromboembolism (VTE)Baseline through Study Completion (Approximately 5.5 Years)

Time from First Dose of Study Treatment to First Event of VTE

Secondary Outcome Measures
NameTimeMethod
Time from First Dose of Study Treatment to First Arterial Thromboembolic Event (ATE)Baseline through Study Completion (Approximately 5.5 Years)

Time from First Dose of Study Treatment to First ATE

Time from First Dose of Study Treatment to First Major Adverse Cerebro-Cardiovascular Event (MACE)Baseline through Study Completion (Approximately 5.5 Years)

Time from First Dose of Study Treatment to First MACE

Time from First Dose of Study Treatment to First Malignancy (excluding nonmelanoma skin cancer [NMSC])Baseline through Study Completion (Approximately 5.5 Years)

Time from First Dose of Study Treatment to First Malignancy (excluding NMSC)

Time from First Dose of Study Treatment to First Opportunistic InfectionBaseline through Study Completion (Approximately 5.5 Years)

Time from First Dose of Study Treatment to First Opportunistic Infection

Time from First Dose of Study Treatment to First Serious InfectionBaseline through Study Completion (Approximately 5.5 Years)

Time from First Dose of Study Treatment to First Serious Infection

Trial Locations

Locations (254)

Medvin Clinical Research - Covina

🇺🇸

Covina, California, United States

Robin K. Dore MD, Inc

🇺🇸

Tustin, California, United States

Medvin Clinical Research - Whittier

🇺🇸

Whittier, California, United States

Great Lakes Clinical Trials

🇺🇸

Chicago, Illinois, United States

Dartmouth-Hitchcock Medical Center

🇺🇸

Lebanon, New Hampshire, United States

PMG Research of Salisbury

🇺🇸

Salisbury, North Carolina, United States

PMG Research of Wilmington, LLC

🇺🇸

Wilmington, North Carolina, United States

REVMACLINIC s.r.o.

🇨🇿

Brno, Jihomoravský Kraj, Czechia

CHU de Nice

🇫🇷

Nice, Alpes-Maritimes, France

Bordeaux University Hospital - Pellegrin

🇫🇷

Bordeaux, Aquitaine, France

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu

🇫🇷

Nantes, Loire-Atlantique, France

Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois

🇫🇷

Vandoeuvre lès Nancy, Meurthe-et-Moselle, France

Centre Hospitalier Régional Universitaire de Lille - Hôpital Roger Salengro

🇫🇷

Lille, France

Debreceni Egyetem - Kenézy Gyula Egyetemi Oktatókórház

🇭🇺

Debrecen, Hungary

Ospedale Luigi Sacco

🇮🇹

Milan, Milano, Italy

Centro poliklinika

🇱🇹

Vilnius, Lithuania

Respublikin Šiauli ligonin

🇱🇹

Siauliai, Šiauliai, Lithuania

Szpital Uniwersytecki Nr 2 w Bydgoszczy, Klinika Reumatologii i Ukladowych Chorób Tkanki Lacznej

🇵🇱

Bydgoszcz, Kujawsko-pomorskie, Poland

GCM Medical Group, PSC - Hato Rey Site

🇵🇷

San Juan, Puerto Rico

First Moscow State Medical University I.M. Sechenov

🇷🇺

Moscow, Moskovskaya Oblast', Russian Federation

Ryazan Regional Clinical Cardiological Dispensary

🇷🇺

Ryazan, Ryazanskaya Oblast', Russian Federation

Complejo Hospitalario Universitario A Coruña

🇪🇸

A Coruña, A Coruña [La Coruña], Spain

Hu Reina Sofia

🇪🇸

Cordoba, Córdoba, Spain

Hospital Universitario Puerta de Hierro Majadahonda

🇪🇸

Majadahonda, Madrid, Comunidad De, Spain

Eskisehir Osmangazi University

🇹🇷

Eskisehir, Eskişehir, Turkey

Izmir Katip Celebi Ataturk Egitim Arastirma Hastanesi

🇹🇷

Izmir, Turkey

Arizona Arthritis & Rheumatology Research, PLLC

🇺🇸

Tucson, Arizona, United States

Arthrocare, Arthritiscare & Research Pc

🇺🇸

Gilbert, Arizona, United States

Hope Research Institute

🇺🇸

Phoenix, Arizona, United States

St Joseph Heritage Healthcare

🇺🇸

Fullerton, California, United States

Christine Thai, MD

🇺🇸

Huntington Beach, California, United States

Private Practice - Dr. Christine J. Leehealey

🇺🇸

Irvine, California, United States

Desert Medical Advances

🇺🇸

Rancho Mirage, California, United States

Rheumatology Center of San Diego

🇺🇸

San Diego, California, United States

East Bay Rheumatology Medical Group, Inc

🇺🇸

San Leandro, California, United States

Dan La, MD Inc

🇺🇸

Tujunga, California, United States

Inland Rheumatology & Osteoporosis Medical Group

🇺🇸

Upland, California, United States

Medvin Clinical Research - Weidmann

🇺🇸

Van Nuys, California, United States

Stamford Therapeutics Consortium

🇺🇸

Stamford, Connecticut, United States

Rheumatology Associates of South Florida

🇺🇸

Boca Raton, Florida, United States

Suncoast Research Group

🇺🇸

Miami, Florida, United States

New Horizon Research Center

🇺🇸

Miami, Florida, United States

Suncoast Clinical Research, Inc.

🇺🇸

New Port Richey, Florida, United States

IRIS Research and Development, LLC

🇺🇸

Plantation, Florida, United States

Qps-Mra, Llc

🇺🇸

South Miami, Florida, United States

ForCare Clinical Research

🇺🇸

Tampa, Florida, United States

Arthritis & Rheumatology of Georgia

🇺🇸

Atlanta, Georgia, United States

Arthritis Center of North Georgia

🇺🇸

Gainesville, Georgia, United States

St. Luke's Intermountain Research Center

🇺🇸

Boise, Idaho, United States

Qualmedica Research, LLC

🇺🇸

Evansville, Indiana, United States

Alliance for Multispecialty Research, LLC

🇺🇸

Wichita, Kansas, United States

Center for Arthritis and Osteoporosis

🇺🇸

Elizabethtown, Kentucky, United States

Accurate Clinical Research

🇺🇸

League City, Texas, United States

The Center for Rheumatology and Bone Research

🇺🇸

Wheaton, Maryland, United States

NECCR PrimaCare Research

🇺🇸

Fall River, Massachusetts, United States

University of Michigan

🇺🇸

Brighton, Michigan, United States

West Michigan Rheumatology

🇺🇸

Grand Rapids, Michigan, United States

Advanced Rheumatology, PC

🇺🇸

Okemos, Michigan, United States

StudyMetrix Research

🇺🇸

Saint Peters, Missouri, United States

Clinvest Research LLC

🇺🇸

Springfield, Missouri, United States

Glacier View Research Institute

🇺🇸

Kalispell, Montana, United States

Albuquerque Center for Rheumatology

🇺🇸

Albuquerque, New Mexico, United States

Physician Research Collaboration, LLC

🇺🇸

Lincoln, Nebraska, United States

Westroads Clinical Research, Inc.

🇺🇸

Omaha, Nebraska, United States

Allied Clinical Research

🇺🇸

Reno, Nevada, United States

Albuquerque Clinical Trials, Inc.

🇺🇸

Albuquerque, New Mexico, United States

Santa Fe Rheumatology

🇺🇸

Santa Fe, New Mexico, United States

Accellacare - Charlotte

🇺🇸

Charlotte, North Carolina, United States

M3-Emerging Medical Research, LLC

🇺🇸

Durham, North Carolina, United States

Piedmont Rheumatology, P.A.

🇺🇸

Hickory, North Carolina, United States

Cape Fear Arthritis Care

🇺🇸

Leland, North Carolina, United States

Cincinnati Rheumatic Disease Study Group

🇺🇸

Cincinnati, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

Paramount Medical Research & Consulting, LLC

🇺🇸

Middleburg Heights, Ohio, United States

Health Research of Oklahoma

🇺🇸

Oklahoma City, Oklahoma, United States

Oklahoma Medical Research Foundation

🇺🇸

Oklahoma City, Oklahoma, United States

East Penn Rheumatology Associates

🇺🇸

Bethlehem, Pennsylvania, United States

Altoona Center For Clinical Research

🇺🇸

Duncansville, Pennsylvania, United States

Clinical Research Center of Reading,LLC

🇺🇸

Wyomissing, Pennsylvania, United States

Pennsylvania Regional Center for Arthritis and Osteoporosis Research

🇺🇸

Wyomissing, Pennsylvania, United States

Regional Health Clinical Research

🇺🇸

Rapid City, South Dakota, United States

Accurate Clinical Management

🇺🇸

Sugar Land, Texas, United States

Arthritis & Osteoporosis Clinic of Brazos Valley

🇺🇸

College Station, Texas, United States

Biopharma Informatic, LLC

🇺🇸

Houston, Texas, United States

DM Clinical Research/Rheumatology Clinic of Houston

🇺🇸

Houston, Texas, United States

Accurate Clinical Management - Houston

🇺🇸

Houston, Texas, United States

Laila A Hassan, MD, PA

🇺🇸

Houston, Texas, United States

Accurate Clinical Research, Inc.

🇺🇸

San Antonio, Texas, United States

Clinical Trials of Texas, Inc.

🇺🇸

San Antonio, Texas, United States

Dynamed Clinical Research, LP d/b/a DM Clinical Research

🇺🇸

Tomball, Texas, United States

Arthritis Northwest, PLLC

🇺🇸

Spokane, Washington, United States

Genesis Research Services

🇦🇺

Newcastle, New South Wales, Australia

The Vancouver Clinic

🇺🇸

Vancouver, Washington, United States

CAMC Health Education and Research Institute Inc

🇺🇸

South Charleston, West Virginia, United States

Optimus Clinical Research

🇦🇺

Botany, New South Wales, Australia

Rheumatology Research Unit

🇦🇺

Maroochydore, Queensland, Australia

Southern Clinical Research

🇦🇺

Hobart, Tasmania, Australia

Emeritus Research

🇦🇺

Camberwell, Victoria, Australia

Medizinische Universität Wien

🇦🇹

Vienna, Wien, Austria

Wilhelminenspital

🇦🇹

Vienna, Wien, Austria

Rheuma-Zentrum Oberlaa GmbH

🇦🇹

Wien, Austria

Université Libre de Bruxelles - Hôpital Erasme

🇧🇪

Brussels, Bruxelles-Capitale, Région De, Belgium

Reuma Clinic, Locatie Jaarbeurslaan

🇧🇪

Genk, Limburg, Belgium

ZNA Jan Palfijn

🇧🇪

Merksem, Vlaams Gewest, Belgium

Revmacentrum MUDr. Mostera, s.r.o.

🇨🇿

Brno, Brno-město, Czechia

Revmatologie.s.r.o.

🇨🇿

Brno, Brno-město, Czechia

Artroscan, s.r.o.

🇨🇿

Ostrava, Moravskoslezský Kraj, Czechia

INREA s.r.o.

🇨🇿

Ostrava, Ostrava Město, Czechia

ARTHROHELP s.r.o.

🇨🇿

Pardubice, Pardubický Kraj, Czechia

Clintrial s.r.o.

🇨🇿

Praha, Praha 10, Czechia

Revmatologie MUDr. Štejfová

🇨🇿

Praha, Praha 4, Czechia

Revmatologicky ustav

🇨🇿

Praha 2, Praha, Hlavní Mešto, Czechia

Universitaetsklinikum Koeln

🇩🇪

Köln, Nordrhein-Westfalen, Germany

Medical Plus

🇨🇿

Uherske Hradiste, Zlínský Kraj, Czechia

PV Medical Services s.r.o.

🇨🇿

Zlín, Zlínský Kraj, Czechia

Affidea Praha, s.r.o.

🇨🇿

Praha 11, Czechia

Revmatologicka ambulance

🇨🇿

Praha 4, Czechia

Regionshospitalet Silkeborg

🇩🇰

Silkeborg, Midtjylland, Denmark

Reumatologisk Ambulatorie, Svendborg Hospital Odense Universitet Hospital

🇩🇰

Svendborg, Syddanmark, Denmark

CHU Strasbourg-Hautepierre

🇫🇷

Strasbourg, Alsace, France

Centre Hospitalier Regional D'Orleans

🇫🇷

Orléans, Centre, France

Hôpital Pierre-Paul Riquet

🇫🇷

Toulouse, Haute-Garonne, France

Hôpital Edouard Herriot

🇫🇷

Lyon, Rhône-Alpes, France

CHD Vendee

🇫🇷

La Roche-sur-Yon, Vendée, France

Infirmerie Protestante de Lyon

🇫🇷

Caluire et Cuire, France

Pitie Salpetriere University Hospital

🇫🇷

Paris, France

CIRI- Center of Innovative Diagnostics and Therapeutics Rheumatology/Immunology

🇩🇪

Frankfurt, Hessen, Germany

Rheumazentrum Prof.Neeck MVZ

🇩🇪

Bad Doberan, Mecklenburg-Vorpommern, Germany

Rheumazentrum Ratingen Studienambulanz

🇩🇪

Ratingen, Nordrhein-Westfalen, Germany

Institut für Präventive Medizin & Klinische Forschung GbR

🇩🇪

Magdeburg, Sachsen-Anhalt, Germany

Praxis für Rheumatologie und Innere

🇩🇪

Berlin, Germany

Schlosspark Klinik

🇩🇪

Berlin, Germany

HRF II - Hamburger Rheuma Forschungszentrum II MVZ für Rheumatologie und Autoimmunmedizin Hamburg GmbH / -T

🇩🇪

Hamburg, Germany

Hamburger Rheuma Forschungszentrum I / Dres Raabe & Heintz

🇩🇪

Hamburg, Germany

Attikon General University Hospital

🇬🇷

Chaidari, Attikí, Greece

Ippokrateio General Hospital of Thessaloniki

🇬🇷

Thessaloniki, Kentrikí Makedonía, Greece

University Hospital of Alexandroupolis

🇬🇷

Alexanroupolis, Évros, Greece

CRU Hungary Kft.

🇭🇺

Miskolc, Borsod-Abaúj-Zemplén, Hungary

Revita Clinic

🇭🇺

Budapest, Pest, Hungary

Clinexpert Kft.

🇭🇺

Budapest, Pest, Hungary

Vital Medical Center

🇭🇺

Veszprem, Veszprém City, Hungary

Debreceni Egyetem Klinikai Kozpont

🇭🇺

Debrecen, Hungary

Barzilai Medical Center

🇮🇱

Ashkelon, HaDarom, Israel

Meir Medical Center

🇮🇱

Kfar Saba, HaMerkaz, Israel

Sheba Medical Center

🇮🇱

Ramat Gan, HaMerkaz, Israel

Sourasky Medical Center

🇮🇱

Tel Aviv, Tell Abīb, Israel

Rambam Health Care Campus

🇮🇱

Haifa, Ḥeifā, Israel

Carmel Hospital

🇮🇱

Haifa, Ḥeifā, Israel

Azienda Ospedaliera Universitaria Careggi

🇮🇹

Firenze, Italy

University of Campania Luigi Vanvitelli

🇮🇹

Napoli, Italy

Policlinico GB Rossi Borgo Roma

🇮🇹

Verona, Italy

Republican Hospital of Kaunas

🇱🇹

Kaunas, Kauno Miestas, Lithuania

Bnai Zion Medical Center

🇮🇱

Haifa, Ḥeifā, Israel

Clinical Research Center - Universita Degli Studi Gabriele d'Annunzio

🇮🇹

Chieti, Abruzzo, Italy

Ospedale Le Scotte

🇮🇹

Siena, Toscana, Italy

Medische Centrum Leeuwarden

🇳🇱

Leeuwarden, Fryslân, Netherlands

PT&R / PreCare Trial & Recruitment

🇳🇱

Born, Limburg, Netherlands

MICS Centrum Medyczne Torun

🇵🇱

Torun, Kujawsko-pomorskie, Poland

Samodzielny Publiczny Zespol Opieki Zdrowotnej W Tomaszowie Lubelskim

🇵🇱

Tomaszów Lubelski, Lubelskie, Poland

Twoja Przychodnia Centrum Medyczne Nowa Sol

🇵🇱

Nowa Sol, Lubuskie, Poland

NZOZ Lecznica MAK-MED s.c.

🇵🇱

Nadarzyn, Mazowieckie, Poland

Medycyna Kliniczna

🇵🇱

Warszawa, Mazowieckie, Poland

Rheuma Medicus- Zak��ad Opieki Zdrowotnej

🇵🇱

Warszawa, Mazowieckie, Poland

Centrum Medyczne Reuma Park

🇵🇱

Warszawa, Mazowieckie, Poland

ETG Warszawa

🇵🇱

Warszawa, Mazowieckie, Poland

Centrum Medyczne AMED Warszawa Targowek

🇵🇱

Warszawa, Mazowieckie, Poland

Osteo Medic sc A. Racewicz, J. Supronik

🇵🇱

Bialystok, Podlaskie, Poland

Ambulatorium Barbara Bazela

🇵🇱

Elblag, Warmińsko-mazurskie, Poland

Ai Centrum Medyczne Sp. Z O.O. Sp.K.

🇵🇱

Poznan, Wielkopolskie, Poland

Centrum Badan Klinicznych PI-House sp. z o.o.

🇵🇱

Gdansk, Pomorskie, Poland

Prywatna Praktyka Lekarska Prof. UM dr hab. med. Pawel Hrycaj

🇵🇱

Poznan, Wielkopolskie, Poland

BIF-MED

🇵🇱

Bytom, Śląskie, Poland

Centrum Medyczne Pratia Katowice

🇵🇱

Katowice, Śląskie, Poland

Centro Reumatologico Caguas

🇵🇷

Caguas, Puerto Rico

Slaskie Centrum Reumatologii, Rehabilitacji I Zapobiegania Niepelnosprawnosci Im. Gen.J.Zietka

🇵🇱

Ustron, Śląskie, Poland

Ponce Medical School Foundation Inc.

🇵🇷

Ponce, Puerto Rico

Latin Clinical Trial Center

🇵🇷

San Juan, Puerto Rico

Mindful Medical Research

🇵🇷

San Juan, Puerto Rico

C.M.D.T.A. Neomed

🇷🇴

Brasov, Brașov, Romania

Cmi Cristei Dorica

🇷🇴

Braila, Brăila, Romania

Spital Clinic Sf. Maria

🇷🇴

Bucharest, București, Romania

Delta Health Care

🇷🇴

Bucharest, București, Romania

CCBR Clinical Research

🇷🇴

Bucuresti, București, Romania

Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei

🇷🇴

Galati, Galați, Romania

RK Medcenter

🇷🇴

Iasi, Iași, Romania

Spitalul Judeean de Urgen Dr. Constantin Opri Baia Mare

🇷🇴

Baia Mare, Maramureș, Romania

Sc Medaudio-Optica Srl

🇷🇴

Râmnicu Vâlcea, Vâlcea, Romania

Gbuz Lokb

🇷🇺

Saint-Petersburg, Leningradskaya Oblast', Russian Federation

Kursk Regional Clinical Hospital

🇷🇺

Kursk, Kurskaya Oblast', Russian Federation

Moscow Clinical Research Center

🇷🇺

Moscow, Moskva, Russian Federation

Federal State Budgetary Scientific Institution Research Institute Rheumatology named after V.A.Nasonova

🇷🇺

Moscow, Moskva, Russian Federation

M. F. Vladimirskiy Moscow Regional Research Clinical Institute

🇷🇺

Moscow, Moskva, Russian Federation

Nizhny Novgorod City Clinical Hospital Number 5

🇷🇺

Nizhny Novgorod, Nizhegorodskaya Oblast', Russian Federation

Clinical Rheumatology hospital #25

🇷🇺

Saint-Petersburg, Sankt-Peterburg, Russian Federation

North-Western State Medical University named after I.I.Mechnikov

🇷🇺

Saint-Petersburg, Sankt-Peterburg, Russian Federation

Tula Regional Clinical Hospital

🇷🇺

Tula, Tul'skaya Oblast', Russian Federation

GUZ UOKB

🇷🇺

Ulianovsk, Ul'yanovskaya Oblast', Russian Federation

Karelia Republican Hospital V.A. Baranova

🇷🇺

Petrozavodsk, Russian Federation

Regional Clinical Hospital of the Saratov Region

🇷🇺

Saratov, Russian Federation

Research & Practice

🇷🇺

Yaroslavl, Russian Federation

ALBAMED s.r.o.

🇸🇰

Zvolen, Banskobystrický Kraj, Slovakia

ROMJAN s.r.o.

🇸🇰

Bratislava, Bratislavský Kraj, Slovakia

Artromac n.o.

🇸🇰

Kosice, Košický Kraj, Slovakia

REUMED s.r.o.

🇸🇰

Spisska Nova Ves, Košický Kraj, Slovakia

LERAM s.r.o.

🇸🇰

Topolcany, Nitriansky Kraj, Slovakia

Reumacentrum s.r.o.

🇸🇰

Partizanske, Trenčiansky Kraj, Slovakia

Netcare Greenacres Hospital

🇿🇦

Port Elizabeth, Eastern Cape, South Africa

FARMOVS

🇿🇦

Bloemfontein, Free State, South Africa

Iatros International

🇿🇦

Bloemfontein, Free State, South Africa

Clinresco Centres

🇿🇦

Kempton Park, Gauteng, South Africa

University of Pretoria - Faculty of Health Sciences

🇿🇦

Pretoria, Gauteng, South Africa

Netcare Umhlanga Hospital

🇿🇦

Umhlanga, Kwazulu-Natal, South Africa

Precise Clinical Solutions

🇿🇦

Chatsworth, Kwazulu-Natal, South Africa

Arthritis Clinical Trial Centre

🇿🇦

Cape Town, Western Cape, South Africa

Winelands Medical Research Centre

🇿🇦

Stellenbosch, Western Cape, South Africa

Clínica Gaias - Santiago

🇪🇸

Santiago de Compostela, A Coruña [La Coruña], Spain

Hospital General Universitario de Elche

🇪🇸

Elche, Alicante, Spain

Hospital Marina Baixa

🇪🇸

Villajoyosa, Alicante, Spain

Clínica Sagrada Familia

🇪🇸

Barcelona, Catalunya [Cataluña], Spain

Hospital Quiron Barcelona

🇪🇸

Barcelona, Catalunya [Cataluña], Spain

Corporació Sanitària Parc Taulí

🇪🇸

Sabadell, Catalunya [Cataluña], Spain

Hospital Clínic de Barcelona

🇪🇸

Barcelona, Catalunya [Cataluña], Spain

Consorci Sanitari Integral. Hospital Moisés Broggi, Sant Joan Despí

🇪🇸

Sant Joan Despí, Catalunya [Cataluña], Spain

CHUS - Hospital Clinico Universitario

🇪🇸

Santiago de Compostela, Galicia [Galicia], Spain

Hospital Universitario de Fuenlabrada

🇪🇸

Fuenlabrada, Madrid, Comunidad De, Spain

Hospital Universitario Getafe

🇪🇸

Getafe, Madrid, Comunidad De, Spain

Osi Bilbao-Basurto

🇪🇸

Bilbo, País Vasco, Spain

CHUVI- Hospital do Meixoeiro

🇪🇸

Vigo, Pontevedra [Pontevedra], Spain

Hospital Quirónsalud Córdoba

🇪🇸

Córdoba, Spain

Hospital Universitario 12 de Octubre

🇪🇸

Madrid, Spain

Hospital Universitario La Paz

🇪🇸

Madrid, Spain

Hospital Universitario Virgen Macarena

🇪🇸

Sevilla, Spain

Hospital Quiron Infanta Luisa

🇪🇸

Sevilla, Spain

The Royal Cornwall Hospital

🇬🇧

Truro, England, United Kingdom

University Hospital Basel

🇨🇭

Basel, Basel-Stadt, Switzerland

Cantonal Hospital St.Gallen

🇨🇭

St. Gallen, Sankt Gallen, Switzerland

HFR Fribourg - Hôpital Cantonal

🇨🇭

Fribourg, Switzerland

Marmara Universitesi Pendik Egitim Arastirma Hastanesi

🇹🇷

Stanbul, İstanbul, Turkey

Trakya University

🇹🇷

Edirne, Turkey

Istanbul University Cerrahpasa Medical School Internal Diseases Institute

🇹🇷

Istanbul, Turkey

Necmettin Erbakan Meram Medical Fac.

🇹🇷

Konya, Turkey

Christchurch Hospital

🇬🇧

Christchurch, Bournemouth, United Kingdom

Derriford Hospital

🇬🇧

Plymouth, Devon, United Kingdom

Torbay Hospital

🇬🇧

Torquay, Devon, United Kingdom

The Dudley Group NHS Foundation Trust

🇬🇧

Dudley, England, United Kingdom

Royal Free London NHS Foundation Trust

🇬🇧

London, England, United Kingdom

Mid Essex Hospital Services NHS Trust

🇬🇧

Chelmsford, Essex, United Kingdom

Queen Alexandra Hospital

🇬🇧

Portsmouth, Hampshire, United Kingdom

Hull and East Yorkshire Hospitals NHS Trust

🇬🇧

Hull, Kingston Upon Hull, United Kingdom

Northumbria Healthcare NHS Foundation Trust

🇬🇧

Newcastle upon Tyne, North Tyneside, United Kingdom

King's Mill Hospital

🇬🇧

Sutton In Ashfield, Nottinghamshire, United Kingdom

Barts Health NHS Trust - Whipps Cross University Hospital

🇬🇧

London, Waltham Forest, United Kingdom

Aintree University Hospital NHS Foundation Trust

🇬🇧

Liverpool, United Kingdom

New Cross Hospital

🇬🇧

Wolverhampton, United Kingdom

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