The Role of Oseltamivir During Influenza Outbreaks in Aged-care Facilities in the Context of Optimal Influenza Vaccination and Infection Control

Phase 3

Not yet recruiting

• Conditions: Influenza in Residential Aged Care Facilities; Surveillance systems for influenza in Residential Aged Care Facilities; Infection - Other infectious diseases; Public Health - Health service research

• Registration Number: ACTRN12615000638538
• Lead Sponsor: Children's Hospital, Westmead: National Centre for Immunisation Research and Surveillance

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-06-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

Any participating residential aged care facility (ACF) from whom written consent has been obtained is eligible to receive the randomly assigned intervention.

Exclusion Criteria

*Subjects who have a known hypersensitivity to oseltamivir or any of its components (see Appendix)
*ACFs who withhold consent
*Residents or staff who have had symptoms suggestive of influenza for longer than 72 hours, as from then there is no *Staff who are pregnant or currently breastfeeding.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Attack rate of Influenza in Treatment and Prophylaxis vs. Treatment only Aged Care Facilities; each positive case will be diagnosed by rapid point-of-care bedside testing, and a subset of these will have laboratory PCR confirmation<br>[At the end of the influenza season: usually 8-12 weeks]