跳至主要内容
临床试验/NCT06088641
NCT06088641进行中(未招募)不适用

Prognostic Impact of Preoperative B-type Natriuretic Peptide for Predicting Myocardial Injury After Non-cardiac Surgery in Patients Who Underwent Open Repair for Abdominal Aortic Aneurysm: a Retrospective Study

Gangnam Severance Hospital1 个研究点 分布在 1 个国家目标入组 198 人开始时间: 2022年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
198
试验地点
1
主要终点
MINS

研究概览

简要总结

The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.

详细描述

The incidence of MINS was compared between the lower BNP and higher BNP groups, and a stepwise logistic regression analysis was performed to evaluate the predictors for MINS.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients who underwent open repair with AAA from September 2010 to October 2021

排除标准

  • Ruptured AAA
  • Traumatic aortic injury
  • Absence of troponin-T value within 30 days of surgery
  • Diagnosis of elevation of troponin-T due to non-ischemic cause (ex: sepsis, pulmonary embolism, atrial fibrillation, cardioversion, etc.)
  • Insufficient medical records

结局指标

主要结局

MINS

时间窗: 30 days after surgery

MINS is defined as an elevated Troponin-T within 30 days of surgery. The patients were divided into two groups based on their preoperative BNP levels, and the incidence of MINS was compared between the two groups.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sung Yeon Ham

professor

Gangnam Severance Hospital

研究点 (1)

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