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Clinical Trials/NCT06088641
NCT06088641
Active, not recruiting
Not Applicable

Prognostic Impact of Preoperative B-type Natriuretic Peptide for Predicting Myocardial Injury After Non-cardiac Surgery in Patients Who Underwent Open Repair for Abdominal Aortic Aneurysm: a Retrospective Study

Gangnam Severance Hospital1 site in 1 country198 target enrollmentJanuary 1, 2022
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ConditionsMyocardial Injury After Non-cardiac Surgery

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myocardial Injury After Non-cardiac Surgery
Sponsor
Gangnam Severance Hospital
Enrollment
198
Locations
1
Primary Endpoint
MINS
Status
Active, not recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.

Detailed Description

The incidence of MINS was compared between the lower BNP and higher BNP groups, and a stepwise logistic regression analysis was performed to evaluate the predictors for MINS.

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
July 6, 2024
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sung Yeon Ham

professor

Gangnam Severance Hospital

Eligibility Criteria

Inclusion Criteria

  • •patients who underwent open repair with AAA from September 2010 to October 2021

Exclusion Criteria

  • •Ruptured AAA
  • •Traumatic aortic injury
  • •Absence of troponin-T value within 30 days of surgery
  • •Diagnosis of elevation of troponin-T due to non-ischemic cause (ex: sepsis, pulmonary embolism, atrial fibrillation, cardioversion, etc.)
  • •Insufficient medical records

Outcomes

Primary Outcomes

MINS

Time Frame: 30 days after surgery

MINS is defined as an elevated Troponin-T within 30 days of surgery. The patients were divided into two groups based on their preoperative BNP levels, and the incidence of MINS was compared between the two groups.

Study Sites (1)

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