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Preoperative BNP and MINS in AAA Open Repair

Active, not recruiting
Conditions
Myocardial Injury After Non-cardiac Surgery
Interventions
Diagnostic Test: preoperative BNP value
Registration Number
NCT06088641
Lead Sponsor
Gangnam Severance Hospital
Brief Summary

The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.

Detailed Description

The incidence of MINS was compared between the lower BNP and higher BNP groups, and a stepwise logistic regression analysis was performed to evaluate the predictors for MINS.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
198
Inclusion Criteria

patients who underwent open repair with AAA from September 2010 to October 2021

Exclusion Criteria
  1. Ruptured AAA
  2. Traumatic aortic injury
  3. Absence of troponin-T value within 30 days of surgery
  4. Diagnosis of elevation of troponin-T due to non-ischemic cause (ex: sepsis, pulmonary embolism, atrial fibrillation, cardioversion, etc.)
  5. Insufficient medical records

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Higher BNPpreoperative BNP valuepreoperative higher BNP
Lower BNPpreoperative BNP valuepreoperative Lower BNP
Primary Outcome Measures
NameTimeMethod
MINS30 days after surgery

MINS is defined as an elevated Troponin-T within 30 days of surgery. The patients were divided into two groups based on their preoperative BNP levels, and the incidence of MINS was compared between the two groups.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Gangnam severance Hospital

🇰🇷

Seoul, Korea, Republic of

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