Effect of Aerobic Training Versus Resistance Training on Plasma Homocystiene in Diabetic Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- homocystiene
研究概览
简要总结
The goal of this [clinical trial] is to [ compare ] in [ diabetic male patients ]. The main question to answer is :
Will be any difference between aerobic exercises and resistance exercises in improving levels of homocysteine, cholesterol and insulin in diabetic patients?
Participants will take their medications and group of them do aerobic exercises and another group do resistance training
详细描述
40 male diabetic patients diagnosed by type 2 diabetes mellites to evaluate therapeutics outcomes of aerobic exercises versus resistance exercises as a treatment tool on homocysteine, insulin and cholesterol levels in diabetic patients.
The patients will be randomly assigned to two equal (in number) groups:
Group (A) Twenty male patients will receive moderate intensity aerobic exercises in a form of supervised treadmill walking for 30-45 mins performed 3 times/ week for 12 weeks.
Group (B) Twenty male patients will receive resistance training program comprised 30-45 min performed 3 times /week for 12 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •1- Their ages will range from 40 -55 years 2- Their body mass indexes will range between (25 to 35 Kg / m²). 3-All patients are diagnosed with type 2 diabetes mellites.
- •Diagnostic criteria for type 2 diabetes were: 1) a fasting plasma glucose concentration of 7.0 mmol·L-1 or higher or 2) a plasma glucose concentration of 11.1 mmol·L-1 or higher two hours after an oral glucose challenge. (Punthakee et al.,2018).
- •All subjects took oral hypoglycemic drugs but none of them were being treated with insulin when enrolled.
- •4- All patients are medically and psychologically stable
排除标准
- •Patients with uncontrolled blood glucose level
- •Patients with unstable cardiovascular conditions (those with a known history of uncontrolled hypertension, ischemic attacks, stroke, congestive heart failure, currently on anticoagulation therapy) were excluded from this study.
- •Patients with severe pulmonary disease (with restrictive lung disease or with obstructive lung disease).
- •Patients with musculoskeletal disorders (Diagnosed with severe osteoporosis or severe osteoarthritis).
- •Patients with BMI > 35 will be excluded from the study.
结局指标
主要结局
homocystiene
时间窗: 12 weeks of training
Homocysteine was measured with an enzyme linked immunosorbent (ELISA) method. The upper limit of normal is 15 μmol/l
次要结局
- insulin(12 weeks of training)
- cholestrol(12 weeks of trianing)
研究者
hanan hassan
Assistant lecturer
Egyptian Chinese University