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Efficacy of Mini Sling Versus Transobturator Tape in Surgical Management of Women With Stress Urinary Incontinence

Not Applicable
Not yet recruiting
Conditions
Stress Urinary Incontinence
Interventions
Procedure: transobturator tape
Registration Number
NCT06334848
Lead Sponsor
Ain Shams University
Brief Summary

To compare the efficacy of mini sling against Transobturator tape for surgical management of women with stress urinary incontinence.

Detailed Description

Urinary incontinence is defined as involuntary loss of urine and is divided into subtypes according to symptoms. These subtypes include SUI, in which urine loss occurs during exertion, physical exercise, coughing or sneezing; urgency urinary incontinence (UUI), in which urine loss is associated with urinary urgency; and mixed urinary incontinence (MUI), which is characterized by the association of stress loss with urgency.

There are non-surgical treatments (e.g., lifestyle modifications, pharmacotherapy, physiotherapy and vaginal pessary) and surgical treatments.

As regards sling use, it was found that mid urethral slings techniques achieved high cure rates in women with SUI and have become the mainstay for surgical treatment of SUI in women over the last 2 decades.

One of the modalities of such procedures is the transobturator mid urethral tape (TOT). It was introduced to minimize the complications of the previous retropubic tapes, which include injury to the bladder, major vessels, and bowel.

In an effort to maintain efficacy while eliminating some of the side effects, a new generation of tapes has been developed, called single incision tapes or mini-slings. They are designed to be shorter in length than standard mid-urethral slings and do not penetrate the tissues as deeply as standard slings.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
Female
Target Recruitment
42
Inclusion Criteria
  • Women with a medical history of SUI
  • mixed urinary incontinence (MUI) in which SUI had to be the dominating symptom
  • confirmed by a positive standardized cough test with 300 cm3 water in the bladder
Exclusion Criteria
  • Women will be excluded if they are aged >60 years
  • had previous incontinence or pelvic organ prolapse surgery
  • planned or present pregnancy
  • residual urine volume>100 ml
  • previous pelvic irradiation
  • neurological conditions such as multiple sclerosis
  • current treatment with corticoids
  • history of genital or abdominal cancer or a pelvic mass.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
treatment of stress urinary incontinence by transobturator tapetransobturator tapepatients with stress urinary incontinence are treated by transobturator tape
treatment of stress urinary incontinence by mini slingtransobturator tapepatients with stress urinary incontinence are treated by mini sling
Primary Outcome Measures
NameTimeMethod
Comparing Mini Sling and Transobturator Tape in Surgical Management of Women with Stress Urinary Incontinence regarding postoperative painone year

comparing between mini sling and transobturator tape in surgical management of women with stress urinary incontinence regarding:

• Post operative pain measured by NRS(numerical rating pain score)

Comparing Mini Sling and Transobturator Tape in Surgical Management of Women with Stress Urinary Incontinence regarding incidence of complicationsone year

comparing between mini sling and transobturator tape in surgical management of women with stress urinary incontinence regarding:

• Urinary continence measured by ICIQ(international continence index questionnaire)

Secondary Outcome Measures
NameTimeMethod
Comparing Mini Sling and Transobturator Tape in Surgical Management of Women with Stress Urinary Incontinence regarding sexual functionone year

comparing between mini sling and transobturator tape in surgical management of women with stress urinary incontinence regarding:

• Sexual function measured by FSFI(female sexual function index)

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