Glycemic variability from switching to steady state in patients treated with long-acting insulin: randomised crossover study
Not Applicable
- Conditions
- type 2 diabetes
- Registration Number
- JPRN-UMIN000032856
- Lead Sponsor
- Inuyama Chuo General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
severe renal dysfunction (serum creatinine level over 2.0 mg/dL) judged to be unsuitable for participation for medical reasons
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean of daily difference 1 (MODD1)
- Secondary Outcome Measures
Name Time Method Multiple continuous overlapping net glycemic action 24 (MCONGA24) (original index) Standard deviation of daily difference (SDODD) (original index) Mean of daily difference (MODD) (day before switching vs. first day, second day vs. third day, fifth day vs. sixth day) continuous overlapping net glycemic action 24 (CONGA24) (day before switching vs. first day, second day vs. third day, fifth day vs. sixth day) Mean absolute glucose (MAG) during evaluation duration (for 7 days) Glycemic variability percentage (GVP) during evaluation duration (for 7 days) Mean glucose level during evaluation duration (for 7 days) Standard deviation (SD) during evaluation duration (for 7 days) Coefficient of variation (CV) during evaluation duration (for 7 days) We investigated the relationship between glycemic diurnal variation (MAG, GVP, mean glucose level, and SD) and glycemic daily variation (MODD and CONGA24) using simulated CGM profiles measured every 15 minute for 24 hours.