Comparison of two blood tests in predicting risk of death in patients with blood infection

Not yet recruiting

• Conditions: Sepsis, unspecified organism,

• Registration Number: CTRI/2018/08/015371
• Lead Sponsor: ALL INDIA INSTITUTE OF MEDICAL SCIENCES

Brief Summary

IN ALL PATIENTS MEETING THE INCLUSION CRITERIA A BLOOD SAMPLE WILL BE DRAWN AND INITIAL SERUM LACTATE AS WELL AS NEUTOPHIL LYMPHOCYTE COUNT RATIO AT THE TIME OF PRESENTATION WILL BE CALCULATED.  AT 6 HOURS INTERVAL OF PRESENTATION SERUM LACTATE VALUE WILL BE MEASURED . LACTATE CLEARANCE WILL BE CALCULATED . THE ABILITY OF LACTATE CLEARANCE AND NEUTROPHIL LYMPHOCYTE COUNT RATIO IN PREDICTING 28 DAYS MORTALITY WILL BE COMPARED AND CORRELATION BETWEEN THEM ASSESSED.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-24
• Last Update Posted: 2018-10-08

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1.PATIENTS WITH PRESUMED BACTERIAL SEPSIS (DEFINED AS POSITIVE qSOFA OR INCREASE IN SOFA SCORE BY TWO OR MORE POINTS) AND INITIAL LACTATE VALUE GREATER THAN 2 mmol PER LITRE.

Exclusion Criteria

• PATIENTS WITH ESRD 2.
• PATIENTS ON HEMODIALYSIS AKI ACUTE CEREBROVASCULAR ACCIDENT ACUTE CORONARY SYNDROME ACUTE PULMONARY OEDEMA STATUS ASTHMATICUS SEIZURE TRAUMA UNCONTROLLED HAEMORRHAGE THOSE RECEIVING CORTICOSTEROID.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
28 DAYS MORTALITY DIFFERENCE BETWEEN LACTATE CLEARANCE GREATER THAN 20 PERCENT OF BASELINE VERSUS LESS THAN 20 PERCENT OF BASELINE AND BETWEEN NLR MORE THAN 7 VERSUS LESS THAN 7	28 DAYS

Secondary Outcome Measures

Name	Time	Method
CORRELATION BETWEEN LACTATE CLEARANCE AND NLR	28 DAYS

Trial Locations

Locations (1)

ALL INDIA INSTITUTE OF MEDICAL SCIENCES; 🇮🇳 South, DELHI, India

ALL INDIA INSTITUTE OF MEDICAL SCIENCES

🇮🇳South, DELHI, India

SHIV AKSHAT

Principal investigator

9654465389

drshivakshat@gmail.com