Clinical and Radiographic Evaluation of Xenograft With Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant Placement in Mandibular Molar Extraction Sites: Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Keratinized tissue Width
研究概览
简要总结
The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.
详细描述
The objective of this study will be to compare between xenograft with Alb-PRF gel and xenograft with L-PRF ( L-PRF Block ) in the aspects of :
- Peri-implant vertical defect depth.
- Crestal bone level.
- Bucco-lingual bone width.
- Keratinized tissue width
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion criteria
- •The presence of non-restorable mandibular molar.
- •Patient 18-45 years old
- •Intact buccal and lingual walls
- •Good oral hygiene.
- •Prescence of sufficient restorative space.
- •Jumping gap more than 2 mm.
排除标准
- •Proximity of anatomical structures
- •Acute localized infection (suppuration at the surgical field)
- •Patients on chemotherapy or radiotherapy.
- •Patients who have systemic disorders (diseases) {diabetes mellitus, autoimmune disease, ...etc},
- •Pregnant patients.
- •Smoking and Alcohols.
- •Presence of periapical pathology affecting the neighboring teeth.
研究组 & 干预措施
L-PRF group
Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF ( L-PRF Block )
干预措施: Immediate Implant Placement and L-PRF (Procedure)
Albumin-PRF group
Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel
干预措施: Immediate Implant Placement and Alb-PRF (Procedure)
结局指标
主要结局
Keratinized tissue Width
时间窗: Immediate Post-Operative and 6 months after surgery
Width of Keratinized tissue before and after surgery
Crestal bone level
时间窗: Immediate Post-Operative and 6 months after surgery
distance between implant platform and bone crest
Vertical peri-implant bone level
时间窗: Immediate Post-Operative and 6 months after surgery
the distance between implant platform to the most coronal bone-implant contact
次要结局
- Implant Stability(Immediate Post-Operative and 6 months after surgery)
- Bucco-lingual bone width(Immediate Post-Operative and 6 months after surgery)
研究者
Mostafa Fayed
Demonstrator of Periodontology
Kafrelsheikh University