Progressive Strength in Hand Osteoarthritis

Phase 4

Completed

• Conditions: Hand Osteoarthritis

• Registration Number: NCT02528630
• Lead Sponsor: Federal University of São Paulo

Brief Summary

Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients.

Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients.

Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-10
• Primary Completion: 2015-01
• Study First Submitted: 2015-08-17
• Study First Submitted QC: 2015-08-18
• Study First Posted: 2015-08-19
• Study Completion: 2015-10
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-19
• Last Update Posted: 2017-02-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• diagnostic of hand OA according to american college of rheumatology of at least 1year;
• age over 50 years;
• both genders;
• pain in interphalangeal joints between 3-8 cm on a 10-cm numerical pain scale

Exclusion Criteria

• other joint disease in hands;
• other rheumatic systemic disease;
• surgery in hands or writs;
• exercise or joint injection in hands in the previous 3 months;
• disability to perform the exercises.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in Pain	Baseline, after 6 and 12 weeks	Measured by a numerical pain scale

Secondary Outcome Measures

Name	Time	Method
Change in grip strength	Baseline, after 6 and 12 weeks	Measured by a Grip Hydraulic Hand Dynamometer
Change in pinch stength	Baseline, after 6 and 12 weeks	Measured by pinch gauge dynamometer
Change in hand function	Baseline, after 6 and 12 weeks	Measured by COCHIN questionnaires
Change in Patient satisfaction with treatment	6 and 12 weeks	Measured by a Likert scale

Trial Locations

Locations (1)

Universidade Federal de Sao Paulo; 🇧🇷 Sao Paulo, SP, Brazil