Effects of tapentadol on chronic pain and parameters of central sensitization.

Recruiting

• Conditions: Chronic Pain, Central Sensitization, tapentadol, pregabalin; Chronische Pijn, Centrale Sensitisatie, tapentadol, pregabalin

• Registration Number: NL-OMON20680
• Lead Sponsor: niversity Medical Center Groningen, dept of Anesthesiology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Gender: female

- Age of patients (18-65 years old)

Exclusion Criteria

- No or insufficient understanding of Dutch language.

- Incapacity to follow instructions.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Central Sensitzation parameters<br /><br>- pressure pain threshold (PPT)<br /><br>- pressure pain tolerance threshold (PTT)<br /><br>- conditioned pain modulation (CPM)<br /><br>- size of allodynia<br /><br>- Wind-up ratio (WUR)<br /><br>- Central Sensitization Inventory (CSI)

Secondary Outcome Measures

Name	Time	Method
- Visual Analog Scale (VAS)<br /><br>- Pain Disability Index (PDI)<br /><br>- Pain Catastrophizing Scale (PCS)<br /><br>- Pain Vigilance and Awareness Questionnaire (PVAQ)<br /><br>- Adverse effects of the medications<br /><br>- Dosages of the medication during the treatment period