Effect of Chronotherapy on Blood Pressure - Time of Intake of Blood Pressure Lowering Drugs

Not Applicable

Recruiting

• Conditions: Hypertension; Drug Therapy; Primary Health Care

• Registration Number: NCT05322967
• Lead Sponsor: Vastra Gotaland Region

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-4-4
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Inclusion Criteria:<br><br> - Diagnosis of hypertension<br><br> - Stable antihypertensive treatment at least 8 weeks prior to inclusion<br><br> - One to four antihypertensive drugs<br><br>Exclusion Criteria:<br><br> - Atrial fibrillation/flutter<br><br> - Diabetes<br><br> - Previous stroke or TIA<br><br> - Heart failure<br><br> - Ischemic heart disease<br><br> - Peripheral artery disease<br><br> - Malignant disease with less than one year expected survival<br><br> - Inability to follow study protocol (for instance shift work)

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
24 hours blood pressure changes between 8 and 16 weeks.;Change of dipping of blood pressure between 8 and 16 weeks.

Secondary Outcome Measures

Name	Time	Method
Daytime blood pressure changes between 8 and 16 weeks.;Nighttime blood pressure changes between 8 and 16 weeks.;Office blood pressure changes between 8 and 16 weeks.;Difference in morning surge of blood pressure between 8 and 16 weeks.;Difference in LDL cholesterol levels between 8 and 16 weeks.;Difference in HDL cholesterol levels between 8 and 16 weeks.;Difference in total cholesterol levels between 8 and 16 weeks.;Difference in p-creatinine levels between 8 and 16 weeks.