CTRI/2017/08/009486已完成未知
A study forevaluating different doses of dexmedetomidine in attenuating extubation response in controlled hypertensive patients for surgeries under general anaesthesia
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Controlled hypertensive patients on antihypertensive drugs for surgery under general anaesthesia
- •2. American society of Anesthesiologist physical status II
- •3. Body Mass Index is under 30 Kg/m2
排除标准
- •1. Untreated hypertension
- •2. Users of ACE inhibitors as antihypertensive therapy
- •3. History of severe cardiovascular disease, renal disease, diabetes mellitus, cerebrovascular disease.
- •4. Known hypersensitivity to the drug.
- •5. Difficult airway
- •6. Any patient who receives blood transfusion.
- •7. Patients refusal for participation in the study.
- •8.Patients with ischaemic and/or congestive cardiac disease or abnormal electrocardiography.
- •9. Patients on digoxin, anticonvulsant or psychotropic medicines.
- •10. If bradycardia (heart rate < 50/min) or hypotension (systolic blood pressure < 80 mm of Hg) occurs anytime during study period, patient will be excluded from the study.
- •11. If bispectral index (BIS) > 60 anytime between starting of infusion and extubation, patient to be excluded from the study.
- •12. If systolic blood pressure >180 mm of Hg during study period.
- •13.If surgery is not completed within 10 mintues of starting infusion.
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