A clinical study to evaluate the effect of drug simvastatin in treatment of jaw bone defects in between the teeth.

Phase 3

Not yet recruiting

• Conditions: Intra-bony defects

• Registration Number: CTRI/2018/05/013782
• Lead Sponsor: kommula mani meghana

Brief Summary

This is a randomized controlled clinical trial to evaluate the efficacy of 1.2%simvastatin in management of similar contra lateral intrabony defects. The primary outcome is measured in terms of amount of radiographic bone fill and reduction in the defect depth at 3 and 6 months. Secondary variables are reduction in probing pocket depth(PD), gain in clinical attachment level(CAL), gingival recession(GR) recorded at 3 months and 6 months.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-05-15
• Last Update Posted: 2018-08-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• 1.Age range of 20-65yrs.
• 2.Presence of atleast on tooth on each side of mouth with probing depth and clinical attachment level≥5mm.
• 3.Radiographic evidence of interproximal intra osseous defect depth≥3mm.

Exclusion Criteria

• 1.Uncontrolled periodontitis.
• 2.Pregnancy or lactating women.
• 3.Patients with any systemic disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone fill occurring in the intrabony defects	Bone fill occurring in the intrabony defects | At 3 months and 6 months.
At 3 months and 6 months.	Bone fill occurring in the intrabony defects | At 3 months and 6 months.

Secondary Outcome Measures

Name	Time	Method
1. Reduction in probing depth	2. Clinical attachment level gain

Trial Locations

Locations (1)

vishnu dental college; 🇮🇳 Godavari, ANDHRA PRADESH, India

vishnu dental college

🇮🇳Godavari, ANDHRA PRADESH, India

kommula mani meghana devi

Principal investigator

9441253717

mkommula93@gmail.com