ung cancer rehabilitation and immunotherapy: a pilot randomised controlled trial.

Not Applicable

• Conditions: Physical Medicine / Rehabilitation - Physiotherapy; on-small cell lung cancer; Non-small cell lung cancer; Cancer - Lung - Non small cell

• Registration Number: ACTRN12624001032549
• Lead Sponsor: The University of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-27
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

•People with a histologically confirmed diagnosis of stage IV, inoperable non-small cell lung cancer (NSCLC) and receiving or are planned to commence treatment with immune checkpoint inhibitors (immunotherapy) either alone or in combination with chemotherapy.
•Age > or = 18 years at screening
•Have provided written informed consent for the trial
•Able to read and write English
•Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
•Available for follow up
•Life expectancy greater than 6 months
•Able to access telehealth for exercise classes if that is their preferred method of attending (requires access to a suitable device and internet sufficient for a video call)

Exclusion Criteria

•Patients scheduled to receive or receiving neoadjuvant immunotherapy or chemo-immunotherapy.
•More than six months post commencement of immunotherapy
•Unstable psychiatric, cognitive or substance abuse disorders that would interfere with cooperation with the requirements of the trial
•Concurrent, actively treated other malignancy or history of other malignancy treated within the past year (other than non- melanoma skin cancer or in-situ melanoma)
•Comorbidities preventing participation in land-based exercise
•Have met the exercise guidelines for people with cancer for the past month
•Patients with a documented bone metastasis where the stability poses a risk of injury during the performance of exercise training; as assessed by the treating oncologist or orthopaedic surgeon.

Study & Design

• Study Type: Interventional
• Study Design: Not specified