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A single-institutional retrospective observational study on evaluation of HER2 expression by immunohistochemical staining in unresectable advanced gastric cancer

Not Applicable
Conditions
Gastric Cancer
Registration Number
JPRN-UMIN000047115
Lead Sponsor
Sapporo City General Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
177
Inclusion Criteria

Not provided

Exclusion Criteria

1. Cases in which HER2_IHC has not been performed. 2. Patients judged by the principal investigator to be inappropriate as research subjects.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
HER2 positive rate: sample type (biopsy / surgical specimen) and test submission date (Weekday / Weekend)
Secondary Outcome Measures
NameTimeMethod
1. HER2 positive rate among all study subjects 2. Comparison of HER2 positive rate by sample collection date (WD/WE) for different sample types (biopsy/surgical specimen) 3. Comparison of formalin fixation time by sample collection date (WD/WE) 4. Comparison of formalin fixation time by sample type (biopsy/surgical specimen) 5. Comparison of formalin fixation time in the sample type (biopsy/surgical specimen) according to the sample collection date (WD/WE) 6. Comparison of formalin fixation time and HER2 expression rate by sample type (biopsy/surgical specimen) 7. The difference in formalin fixation time (all population/sample type/sample collection date) 8. Comparison of treatment results by HER2 status (positive/negative) (overall survival from the start of chemotherapy, duration of response to trastuzumab combination therapy, and response rate)
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