Metformin Use and Vitamin B12 Deficiency

Completed

• Conditions: Vitamin B12 Deficiency; Type 2 Diabetes Mellitus

• Registration Number: NCT01136512
• Lead Sponsor: Northwell Health

Brief Summary

The primary objective is to determine the incidence of Vitamin B12 deficiency in patients on metformin therapy for diabetes.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Study First Submitted: 2010-06-02
• Study First Submitted QC: 2010-06-02
• Study First Posted: 2010-06-03
• Status Verified: 2013-07
• Last Update Submitted: 2013-07-29
• Last Update Posted: 2013-07-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 89

Inclusion Criteria

Age 20-80; diagnosed with type 2 diabetes for at least 30 days

Exclusion Criteria

known vitamin B12 or folate deficiency; pernicious anemia; on vitamin B12 therapy; hematological malignancy; methotrexate use; alcohol intake greater than two drinks per day; vegetarian diet; previous gastric surgery; inflammatory bowel disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vitamin B12 level	Single point

Secondary Outcome Measures

Name	Time	Method
methylmalonic acid	single point

Trial Locations

Locations (1)

Staten Island University Hospital; 🇺🇸 Staten Island, New York, United States