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临床试验/NCT01224470
NCT01224470已完成不适用

The Effects of Intravenous Dexmedetomidine on Spinal Anesthesia Using Low Dose Diluted Bupivacaine for Transurethral Resection of Prostate

Yonsei University1 个研究点 分布在 1 个国家目标入组 51 人开始时间: 2010年11月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
51
试验地点
1

研究概览

简要总结

Dexmedetomidine is a new selective and potent alpha-2 agonist. It has centrally acting anesthetic properties. It has been known that intrathecal addition of alpha-2 adrenergic agents result in prolongation of the duration of the sensory and motor blockade induced by hyperbaric bupivacaine. But the effects of intravenous dexmedetomidine on the spinal block was not evaluated. The aim of study is to assess the effect of intravenous dexmedetomidine on the low-dose spinal anesthesia for the transurethral surgery.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • ASA class I or II
  • Elective transurethral prostatectomy
  • aged > 20

排除标准

  • Coagulation deficiency
  • infection on the back
  • Congestive heart failure or arrythmia
  • Chronic alcoholic disease
  • Antidepressants therapy

研究组 & 干预措施

bupivacaine

Active Comparator

0.5% bupivacaine 1.2 mL + normal saline 0.8 mL = total 2 mL

干预措施: Dexmedetomidine (Drug)

saline

Placebo Comparator

干预措施: Dexmedetomidine (Drug)

研究者

申办方类型
Other

研究点 (1)

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