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Measuring and Predicting Glycemic Response to Food in Patients With Type 1 Diabetes

Conditions
Personalized Medicine in Type 1 Diabetes
Registration Number
NCT02919839
Lead Sponsor
Dr. Orit Hamiel
Brief Summary

Personalized medicine methods in the management of type 1 diabetes

Detailed Description

This proposal joins together clinical practitioners, biologists, and computer scientists to set up the infrastructure for research that will facilitate, for the first time, the use of big-data, machine-learning approaches in the application of personalized medicine methods in the management of type 1 diabetes mellitus. We will model the clinical, microbial, and nutritional factors underlying the variability in glycemic response to food in this population; develop algorithms for prediction of this response and for the accurate administration of insulin, assisting the clinical management of the disease and discover intervention targets in the gut microbiome aimed at improving glycemic control.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
200
Inclusion Criteria

over one year of diagnostic with T1DM.

Exclusion Criteria

Drug related diabetes. genetical diabetes.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
blood glucose2 weeks
Secondary Outcome Measures
NameTimeMethod
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