Study on Molecular Basis of Stellate Ganglion Block for Chronic Pai

Not Applicable

Recruiting

• Conditions: Chronic primary orofacial pain, Chronic secondary orofacial pain

• Registration Number: JPRN-UMIN000051995
• Lead Sponsor: Kanagawa Dental University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-08-24
• Last Update Posted: 17 October 2023
• Study Completion: 2027-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Contraindications to SGB, failures of SGB, accidents by SGB, patients with diagnosed psychiatric disorder.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain- and stress-related biomarkers on pre- and post-SGB in saliva (i.e. Brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), cortisol, alpha-amylase, chromogranin A)

Secondary Outcome Measures

Name	Time	Method
Other pain- and stress-related biomarkers in saliva or blood (i.e. serotonin, noradrenaline, interleukin-1beta (IL-1beta), IL-6, IL-8, substance P, endorphin, dehydroepiandrosterone, noradrenaline, tumor necrosis factor (TNF-alpha), prostaglandin, leukotriene, enkephalin, bradykinin, vasopressin)