NCT01377493已完成早期 1 期
Effects of a Chewing Gum Containing POs-Ca and Fluoride on Remineralization of Enamel Subsurface Lesions in Situ
适应症
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 36
- 主要终点
- Mineral content of enamel
研究概览
简要总结
There were no differences in the degree of enamel remineralization of subsurface lesions among the chewing gums containing or not containing POs-Ca and fluoride.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 31 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adult subjects
- •More than 22 permanent teeth
排除标准
- •Alcohol addiction
- •Active caries
- •Periodontal pockets
- •Low-saliva flow (less than 0.3ml/min)
结局指标
主要结局
Mineral content of enamel
时间窗: 2 weeks
Mineral content of bovine enamel blocks inserted into the subject mouth during chewing of the gums was assessed.
次要结局
未报告次要终点
研究者
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