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Clinical Trials/EUCTR2011-000506-21-GB
EUCTR2011-000506-21-GB
Active, not recruiting
Phase 1

A double-blind, randomised placebo-controlled trial to determine whether low-dose intravenous ketamine peri-operatively can prevent chronic post-surgical pain, in patients undergoing thoracotomy or video assisted thoracic surgery (VATS). - RCT of ketamine versus placebo after thoracotomy or VATS surgery (1)

Imperial College Healthcare NHS Trust0 sites104 target enrollmentApril 14, 2011
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ConditionsChronic post-surgical pain
DrugsKetalar

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Chronic post-surgical pain
Sponsor
Imperial College Healthcare NHS Trust
Enrollment
104
Status
Active, not recruiting
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 14, 2011
End Date
July 9, 2015
Last Updated
6 years ago
Study Type
Interventional clinical trial of medicinal product

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. All adult patients (\> 18 years) who are undergoing either thoracotomy or VATS. 2\. Participants must be able to understand English.
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range:
  • •F.1\.2 Adults (18\-64 years) yes
  • •F.1\.2\.1 Number of subjects for this age range
  • •F.1\.3 Elderly (\>\=65 years) yes
  • •F.1\.3\.1 Number of subjects for this age range

Exclusion Criteria

  • •1\. Patient refusal 2\. History of previous chronic thoracic pain 3\. Neuropathic pain (whatever the site), existing at time of recruitment 4\. Pre\-operative analgesic treatments which include the following medications: strong opioids (step 3 analgesics), tricyclic antidepressants, venlafaxine, gabapentin, pregabalin, duloxetine, clonazepam or carbamazepine. 5\. Allergy to bupivacaine, morphine, paracetamol, tramadol, dihydrocodeine or ketamine.

Outcomes

Primary Outcomes

Not specified

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