Effectiveness of Pregabalin on Sleep Quality in Patients Receiving Methadone Maintenance Treatment
Not Applicable
- Conditions
- SUBSTANCE DEPENDENCY.A cluster of behavioural, cognitive, and physiological phenomena that develop after repeated substance use and that typically include a strong desire to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences
- Registration Number
- IRCT2015021121045N1
- Lead Sponsor
- orth khorasan University of Medical Sciences,Deputy of Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
History of heroin dependency; patients under methadone maintenance treatment
Exclusion criteria: Age under 18 year and older than 75; starting methadone maintenance treatment less than 6 month; PSQ sleep quality questionnaire score less than 5; patients with severe sleep disorder who need special treatment or major depressive disorder or psychosis based on psychiatrist visit; Participants with methadone maintenance dose lower than 60 mg/day or higher than 120 mg/day; Participant with using sedative- hypnotic drugs or heroin or methamphetamine during 8 week intervention
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sleep quality. Timepoint: before intervention,week 4,week 8. Method of measurement: Pittsburgh sleep quality questionaire.
- Secondary Outcome Measures
Name Time Method Drug side effects. Timepoint: week 1-8,weekly. Method of measurement: standard side effects checklist.