Ultrasound Guided Serratus Plane Block Versus Thoracic Epidural for Post Thoracotomy Pain: A Prospective Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Score of postoperative pain at rest (Visual Analogue Scale, VAS, pain score).
研究概览
简要总结
This study aims at comparing the effect of serratus plane block versus thoracic epidural in patients undergoing thoracotomy for lung cancer surgery regarding pain control and possible side effects.
详细描述
Introduction:
One of the most painful devastating surgical incisions is post-thoracotomy pain which can occur secondary to skin incision, damage to serratus anterior and intercostal muscles, rib retraction and injury of the intercostal nerves (1). It leads to pulmonary complications in the short term and chronic post-thoracotomy pain in the long term (2). The thoracic epidural is usually used as the reference analgesic approach for controlling thoracotomy pain (3) but it carries several risks and limitations (4). Serratus anterior plane block is performed by blocking the lateral cutaneous branches of the intercostal nerves (5) and can be a possible alternative to epidural block with lesser risks (6).
Aim of the work This study aims at comparing the effect of serratus plane block versus thoracic epidural in patients undergoing thoracotomy for lung cancer surgery regarding pain control and possible side effects.
Authors suggest that this technique is easy to perform, safe, effective with lesser side effects.
Study Design A randomized controlled study. Methodology
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 20 to 60
- •American Society of Anesthesiologists (ASA) physical status I-II grade
- •Body mass index (BMI) < 40 kg/m2
- •Undergoing elective thoracic surgery.
排除标准
- •Coagulation defects
- •Refusal for serratus anterior block
- •Inability to obtain informed consent
- •Local infection at the site of injection
- •Bone metastases
- •Known allergy to any of the used drug
结局指标
主要结局
Score of postoperative pain at rest (Visual Analogue Scale, VAS, pain score).
时间窗: 24 hours postoperative
Scores are based on self-reported measures of symptoms that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no pain" on the left end (0 cm) of the scale and the "worst pain" on the right end of the scale (10 cm)
次要结局
- Amount of postoperative opioid consumption(24 hours postoperative)
- No of patients developed adverse effects.(24 hours postoperative)
- Score of postoperative pain at coughing (Visual Analogue Scale, VAS, pain score)(24 hours postoperative)
研究者
Mamdouhmahmoud
Lecturer
National Cancer Institute, Egypt