Discoloration of Endosequence and Mineral Trioxde Aggregate in Revascularization of Necrotic Immature Permanent Teeth
- Conditions
- Pulp Necrosis
- Interventions
- Other: Revascularization
- Registration Number
- NCT03813433
- Lead Sponsor
- Cairo University
- Brief Summary
the objective of this study is to evaluate post operative pain after using Endosequence versus Mineral Trioxide Aggregate as coronal plug material in revascularization of non vital immature anterior teeth
- Detailed Description
The treatment of immature young permanent anterior teeth is challenging because in addition of the need of elimination of bacterial infection; the lack of natural apical constriction against which a suitable filling material can be placed is considered the main problem.
In the past many different treatments have been proposed for immature permanent teeth with necrotic pulps such as:Custom fitting of filling materials like gutta percha, Periapical surgeries, apexification. The disadvantages of these treatments are: the compromised Crown/root ratio, possibility of vertical fracture.
Pulp revascularization is dependent on the ability of residual pulp and apical and periodontal stem cells to differentiate. These cells have the ability to generate a highly vascularized and rich living tissue.
MTA was chosen as coronal seal to be placed over the blood clot due its a biocompatibility, bio-inductivity. However, the disadvantages of MTA are: discoloration of the coronal dentine when placed in the canal and the difficult handling properties.
Recently, a new bioceramic material has been introduced to the market, namely, EndoSequence which is bioactive, has antibacterial activity, less cytotoxic effect and similar antimicrobial properties, maintain color stability of the tooth when compared to MTA
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 24
- Age of patient range from 8-14 y.
- Patients are free from any systemic diseases that may hinder the normal healing process.
- Non vital permanent anterior teeth with open apex.
- Pulp space not needed for post and core for final restoration.
- Compliant patient/parent.
- Patients having allergy to medicaments and antibiotics necessary to complete the procedure.
- Tooth with vital pulp or complete root formation.
- Teeth with internal or external root resorption.
- Un-cooperative patients
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Mineral Trioxide Aggregate Revascularization 3-4 mm of Mineral Trioxide Aggregate will be applied over the blood clot in group I. Material will be packed using condenser with light pressure. Periapical radiograph will be taken to ensure coronal seal in the second visit of revascularization Enosequence Revascularization 3-4 mm of Endosequence will be applied over the blood clot in group I. Material will be packed using condenser with light pressure. Periapical radiograph will be taken to ensure coronal seal in the second visit of revascularization
- Primary Outcome Measures
Name Time Method discoloration 12months Asking patient question (Binary:present or absent)
dicoloration 6 months Asking patient question (Binary:present or absent)
- Secondary Outcome Measures
Name Time Method Swelling 1,3, 6, 9 and 12 months assessed by visual examination (Binary:present or absent)
Root lengthening 6 and 12 months assessed radiographically (DIGORA® for Windows software)
post operative pain 1,3, 6, 9 and 12 months asking the patient (Binary: present or Absent)
color stability 1,3, 6, 9 and 12 months Operator and supervisor evaluation (Using shade guide)
Sinus or fistula 1,3, 6, 9 and 12 months assessed by visual examination (Binary:present or absent)
Pain on percussion 1,3, 6, 9 and 12 months Assessed by back of the mirror (Binary: present or absent)