Study of age and sex related changes in lipid layer thickness of tear film

Not Applicable

Completed

• Registration Number: CTRI/2020/10/028769
• Lead Sponsor: Shri Kanchi Kamakoti Medical Trust Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-03-31
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

1.Males and females of age group 20-30 years and 50 -60 years

2.Normal subjects will be defined as:

a)SPEED questionnaire score of 0

b)Schirmerâ??s test value of more than 10 seconds after 5 minute

c)Tear film break up time of more than 10 seconds

d)Oxford staining score of grade 0 or grade 1

e)Normal lid margins

f)Patent lacrimal sac apparatus

Exclusion Criteria

1. Subjects found to have abnormal values in the above mentioned tests

2. Undergone refractive or ocular surgery in the past one year

3. Using contact lens

4. Ocular injury/ocular infection in past 6 months

5. Lid margin abnormalities

6. Punctal plugs, punctal occlusion, canalicular and nasolacrimal duct blocks

7. Subjects on any ocular medications

8. Subjects on systemic medications (OCP, antidepressants, antipsychotics, antihistamines )

9. Systemic comorbidities like diabetes mellitus

10. Collagen vascular diseases

11. Auto- immune diseases.

12. Parkinsonâ??s disease.

Study & Design

• Study Type: Observational
• Study Design: Not specified