The Paediatric Obstructive Sleep Apnoea (OSA) Screening Triple Test (POSTT) Study: Validation of a novel home delivered paediatric OSA screening test.

Not Applicable

Conditions: Paediatric Obstructive Sleep Apnoea
Paediatric sleep disordered breathing
Respiratory - Sleep apnoea

Registration Number: ACTRN12624000465550

Lead Sponsor: Monash University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: All

Target Recruitment: 129

Inclusion Criteria

a)Target Population: Australian children aged 2-16 years and at least one parent/guardian
b)Sample Populations:
- Patients, who have already been referred for PSG and fit inclusion criteria, will be recruited from each participating sleep centre.
c)Study participants will be considered eligible for inclusion if they are aged between 2-16 years at the time of recruitment, and able to complete the POSTT within 4 weeks of PSG.

Exclusion Criteria

Exclusion Criteria 1: Based on studies showing reduced accuracy of pulse oximetry testing in these populations, children with the following conditions will be excluded from the study:
a.Neuromuscular disease,
b.Congenital syndromes (e.g. Trisomy 21),
c.Congenital heart diseases,
d.Chronic lung disease requiring oxygen therapy,
e.Previous trauma/burns to airway/face/neck,
f.Weight <3rd or >95th centile for age

Exclusion Criteria 2: Previous adenotonsillectomy (this renders tonsillar size component of index test non-contributory).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and Specificity of POSTT for the prediction of moderate or severe Obstructive Sleep Apnoea will be determined.[Sensitivity of OSA diagnoses will be determined by comparing POSTT results to the gold standard in-lab Polysomnography. The individual results from the McGill Oximetry Grade, Paediatric Sleep Questionnaire (PSQ) and Brodsky Tonsil grade will be combined to produce an Obstructive Sleep Apnoea score (normal/mild vs Moderate /severe), and compared to the Polysomnography Report (normal/mild vs Moderate/severe). <br>Apnoea Hypopnea Index (AHI), McGill Oximetry Grade, Paediatric Sleep Questionnaire (PSQ), Brodsky tonsil grade. POSTT completed on Day 1, and overnight Polysomnography completed within the next 4 weeks.]

Secondary Outcome Measures