A comparison of two techniques for pain relief following Knee Replacement Surgery

Phase 4

• Conditions: Knee Replacement Surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12619000364178
• Lead Sponsor: Mater and St Vincents Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-07
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

Elective primary unilateral total knee arthroplasty
Age 40-75 years
ASA 1-3
Ability to self mobilise

Exclusion Criteria

BMI>40
Previous involvement in this study.
Neuropathic pain or opioid tolerance (defined as use of >30mg oral morphine/day or
equivalent – fentanyl patch 12mcg/hr, buprenorphine patch 20mcg/hr, oral oxycodone
>20mg/day)
History of stroke or major neurological deficit, sensory and motor disorders in the
operated limb
Contraindication to spinal anaesthesia (including coagulopathy, sepsis, local infection,
patient refusal, spinal defects, previous laminectomy, use of anticoagulant/antiplatelet
medications as per ASRA guidelines)
Contraindication to any of the study drugs (including allergy, significant renal or
hepatic disease, NSAID induced asthma)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain Scores via numerical rating scale[maximum score in first 24hr post op (single measurement)];Opioid Consumption as measured by oral morphine dose equivalents of administered opioid.<br>(on review as recorded in medical records)[at 24hr post op (single measurement)]