Dairy Consumption During a High-intensity, High-volume Training Week in Young Athletes
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Brock University
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- Height (cm)
Study Overview
Brief Summary
Our proposed study is a 5-d double-blind randomised cross-over trial, seeking to simulate a training identification camp in competitive adolescent soccer players
The purpose of the proposed study is to investigate whether increased protein consumption by Greek yogurt, compared to an isoenergetic carbohydrate (CHO) control supplement, consumed immediately following exercise training, prior to sleep and between breakfast and lunch, for a week during an intense training period (high volume, high intensity) will:
- Attenuate the pro-inflammatory response (cytokines, acute phase proteins)
- Reduced the severity of muscle damage and impairment (creatine kinase)
- Maintain performance
Secondary outcome measures:
- Increase bone turnover (in favour of formation)
Detailed Description
The proposed study is a randomized, double-blinded, cross-over trial. The protocol will consist of an information session, two identical training camps consisting of 5 consecutive days of intensified soccer training, differing only by nutritional intervention, and identical pre-and post-training session testing. Each testing block will be separated by 28-d to allow for an adequate wash-out and recovery period, during which participants would resume their regular soccer activities
Study Procedures:
All tests and measurements will be performed within eight-weeks. Specifically, participants will attend 1 information session, two identical pre- and post- training/testing sessions and two identical soccer specific training camps.
Information session:
One week prior to the initial soccer specific training camp, participants will be informed of all tests and procedures that will take place and be familiarized with all testing protocols.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 11 Years to 16 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Participant are female within the desired age ranges (11-16y)
- •Participants are competitive soccer players
- •Previous participation in high-performance training environment (periodization)
Exclusion Criteria
- •Participant is not female or falls outside of the desired age ranges (11-16y)
- •Chronic/frequent use of medications that could affect inflammatory function - NSAIDS or Corticosteroids.
- •Musculoskeletal injury - resulting in the inability to train and/or perform the baseline/post testing.
Outcomes
Primary Outcomes
Height (cm)
Time Frame: 8 weeks
Anthropometric measures
Plasma concentrations of CRP (pg/ml)
Time Frame: 8 weeks
Plasma concentrations of pro-and-anti-inflammatory cytokines
Body fat (%)
Time Frame: 8 weeks
Body composition
Serum concentrations of OPG (pg/ml)
Time Frame: 8 weeks
Bone formation marker
Serum concentrations of TRAP (ng/ml)
Time Frame: 8 weeks
Bone resorption marker
Serum concentrations of CTX (ng/ml)
Time Frame: 8 weeks
Bone resorption marker
Body mass (kg)
Time Frame: 8 weeks
Anthropometric measures
Serum concentrations of BAP (ng/ml)
Time Frame: 8 weeks
Bone formation marker
Serum concentrations of PINP (ng/ml)
Time Frame: 8 weeks
Bone formation marker
Serum concentrations of RANKL (pg/ml)
Time Frame: 8 weeks
Bone resorption marker
Plasma concentrations of IL-6 (pg/ml)
Time Frame: 8 weeks
Plasma concentrations of pro-and-anti-inflammatory cytokines
Plasma concentration of creatine kinase (U/L)
Time Frame: 8 weeks
Muscle damage
Seated height (cm)
Time Frame: 8 weeks
Used to calculate maturity offset in years from peak height velocity
Rate of perceived exertion
Time Frame: 8 weeks
1-10 scale of perceived exertion
Plasma concentrations of TNF-alpha (pg/ml)
Time Frame: 8 weeks
Plasma concentrations of pro-and-anti-inflammatory cytokines
Plasma concentrations of irisin (ng/ml)
Time Frame: 8 weeks
Plasma concentrations of pro-and-anti-inflammatory cytokines
Plasma concentrations of IL-10 (pg/ml)
Time Frame: 8 weeks
Plasma concentrations of pro-and-anti-inflammatory cytokines
Secondary Outcomes
- Plasma concentration of ROS(8 weeks)
- Serum concentration of IGF-1 (pg/ml)(8 weeks)
- Plasma concentration of TBARS(8 weeks)
- Saliva concentrations of cortisol (ug/dl)(8 weeks)
- Saliva concentrations of testosterone (pg/ml)(8 weeks)
- Oxidative stress(8 weeks)
Investigators
PKlentrou
Professor and Associate Dean
Brock University