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临床试验/NCT01508351
NCT01508351已完成不适用

The Hypotensive Effect of Propofol: an Observational Study of Hypotension With Anesthetic Induction by Propofol in the General Population Under Standard of Care Anesthesia

Milton S. Hershey Medical Center1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
1
主要终点
The systolic, diastolic, and mean arterial pressure.

研究概览

简要总结

Hypotension is a recognized frequent complication of induction of anesthesia. The intent of this research is to determine the incidence of hypotension in patients receiving anesthetic induction with propofol. This investigation seeks to examine how normal clinical practice or a "real world" understanding of the usual response to propofol affects hemodynamics without isolating or standardizing other variables. The current research concerns hypotension in normal clinical practice where variability exists. This project aims to gather information and data in an attempt to form a foundation upon which each of the other variables affecting blood pressure may be subsequently assessed.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All ASA 1-3 patients who are to receive propofol induction for general anesthesia

排除标准

  • Allergy to propofol
  • ASA 4 and above

结局指标

主要结局

The systolic, diastolic, and mean arterial pressure.

时间窗: Within first 20 minutes after anesthesia induction

The systolic, diastolic, and mean arterial pressure will be measured every minute for twenty minutes. Blood pressure readings of Mean Arterial Pressure less than 65mmHg, Systolic Blood Pressure less than 80mmHg, or Diastolic Blood Pressure less than 40mmHg will be considered as hypotension.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Thomas Verbeek

Assistant Professor, Anesthesiology

Milton S. Hershey Medical Center

研究点 (1)

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