The Use of Noninvasive Brain Stimulation in Post-traumatic Stress Disorder

Not Applicable

• Conditions: Post-traumatic Stress Disorder
• Interventions: Device: Active repetitive Transcranial Magnetic Stimulation; Device: Sham repetitive Transcranial Magnetic Stimulation

• Registration Number: NCT02542709
• Lead Sponsor: Laval University

Brief Summary

The purpose of this trial is to study the effect of noninvasive brain stimulation in adults with post-traumatic stress disorder.

Detailed Description

The purpose of this trial is to study the effect of noninvasive brain stimulation on symptoms severity in adults with post-traumatic stress disorder.

Study Timeline

• Study Start: 2015-03
• Study First Submitted: 2015-03-26
• Status Verified: 2015-09
• Study First Submitted QC: 2015-09-03
• Last Update Submitted: 2015-09-03
• Study First Posted: 2015-09-07
• Last Update Posted: 2015-09-07
• Primary Completion: 2016-03
• Study Completion: 2016-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• 18-60 years old

Exclusion Criteria

• Transcranial magnetic stimulation ineligibility

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Active transcranial magnetic stimulation	Active repetitive Transcranial Magnetic Stimulation	Active transcranial magnetic stimulation will induce real pulses using the transcranial magnetic stimulation device.
Sham transcranial magnetic stimulation	Sham repetitive Transcranial Magnetic Stimulation	Sham transcranial magnetic stimulation will not induce any pulses using the same transcranial magnetic stimulation device but by also adding a sham block device.

Primary Outcome Measures

Name	Time	Method
Severity of symptoms on the following clinical scale: PTSD symptoms as assessed by the Modified PTSD Symptom Scale (MPSS-SR)	2 months	Units will be the differences (%) in scores before and after the intervention

Secondary Outcome Measures

Name	Time	Method
Severity of symptoms on the following clinical scale: depression symptoms as assessed by the Beck Depression Inventory (BDI)	2 months	Units will be the differences (%) in scores before and after the intervention
Severity of symptoms on the following clinical scale: anxiety symptoms as assessed by the Beck Anxiety Inventory (BAI)	2 months	Units will be the differences (%) in scores before and after the intervention

Trial Locations

Locations (1)

IRDPQ; 🇨🇦 Quebec, Canada