Supplemental Thyroxine Treatment for Preterm Infants with Hypothyroxinemia
Not Applicable
- Conditions
- Very low birhth weight infants with thyroxine level less than 0.8 ng/dl at the age of between 2 and 4 weeks after birth
- Registration Number
- JPRN-UMIN000001953
- Lead Sponsor
- Tokyo Women's Medical University
- Brief Summary
The mean plasma concentrations of FT4 showed no significant differences in the 2 groups, whereas the mean plasma concentration of TSH was significantly lower in the treated group, suggesting suppression of TSH secretion after L-T4 administration (P < 0.05). There were no significant differences in growth at 18 months of corrected age. Furthermore, there were no significant differences in the incidence of developmental delay, cerebral palsy, visual impairment, and hearing impairment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
Maternal thyroid diseases TSH more than 10 microunit/ml Sever congenital malformations
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method