Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Mansoura University
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Stone Free rate
Study Overview
Brief Summary
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
Detailed Description
Patients with complete staghorn stones who are eligible to percutaneous nephrolithotomy (PNL) will be randomized between two groups.
Group 1: will undergo Laser lithotripsy during PNL Group 2: will undergo ultrasonic lithotripsy during PNL
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Complete staghorn stones (filling the renal pelvis and branching to 3 major calyces
- •Age: 18-70 years
Exclusion Criteria
- •Congenital renal anomalies such as horse shoe kidney.
- •Contraindications to PNL such as bleeding tendency and uncontrolled hypertension.
- •Associated pathological features requiring open intervention such as UPJO
- •Partial staghorn stones (filling the renal pelvis and branching to 2 major calyces)
- •Giant staghorn stone (very large staghorn stone that branch and re-branch in hugely dilated calyceal system)
Arms & Interventions
Laser
Patients will undergo Laser lithotripsy
Intervention: Laser (Device)
Ultrasonic
Patients will undergo ultrasonic lithotripsy
Intervention: Ultrasonic (Device)
Outcomes
Primary Outcomes
Stone Free rate
Time Frame: Patients will be followed for 3 months after the procedure
Assessment of stone free rate after 3 months from treatment using NCCT
Secondary Outcomes
- Operative time(An expected average of 3 hours)
- Assessment of the safety of each technique(From the start of the operation till 3 months after discharge from the hospital)
- Hospital stay(up to 7 days)
Investigators
Ahmed R. EL-Nahas
Assistant Professor of Urology
Mansoura University