Brain Lesion and Visuospatial Impairment in CP Child

Completed

• Conditions: Children with Cerebral Palsy
• Interventions: Diagnostic Test: PVSE Test; Other: Cerebral MRI

• Registration Number: NCT06131320
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Children with cerebral palsy (CP) show varying degrees of motor impairment and movement disorders whose perceptive-visual contribution has yet to be established. The literature reports that children with CP have more frequent neuro-visual disorders. The link between the location and size of the brain lesion and neurovisual symptomatology has yet to be explored.

In this retrospective clinical data study, we will investigate in children with PC whether there is an anatomo-clinical correlation between visuo-spatial disorders is the brain injury of interest to the dorsal visual pathway. We will explore the volume of grey and white matter parietal involvement.

To test visuo-spatial disorders, we will use the PVSE (Visuo-Spatial Elementary Perception) test which does not require motor skills or language and is therefore suitable for children with a PC. This test will make it possible to better identify the deficit or deficits in order to adapt an early remediation. It could serve as a reference for comparing several pathologies/etiologies.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-01
• Study First Submitted: 2023-11-09
• Study First Submitted QC: 2023-11-09
• Study First Posted: 2023-11-14
• Primary Completion: 2023-12-31
• Study Completion: 2024-04-02
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-07
• Last Update Posted: 2024-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Male or female aged 4 to 18 yo
• With a CP diagnosis
• With PVSE test completion during his/her regular follow-up
• With a cerebral MRI scan during his/her regular follow-up

Exclusion Criteria

• With an incomplete PVSE test or whose interpretation was deemed unreliable by the rater

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CP child	PVSE Test	-
CP child	Cerebral MRI	-
CP child with a PVSE test and a cerebral MRI performed during his/her follow-up	PVSE Test	-
CP child with a PVSE test and a cerebral MRI performed during his/her follow-up	Cerebral MRI	-

Primary Outcome Measures

Name	Time	Method
PVSE test results: total score and 8 sub-scores (length perception, size perception, angle comparison, midline localization, position perception, position selection, occipital score and parietal score.)	At the inclusion	Using normative values of PVSE test, we assess pathological measure inferior outlier limits and subnormal measure below the lower quartile limit

Trial Locations

Locations (1)

Pediatric rehabilitation unit of the Hospices Civils de Lyon; 🇫🇷 Bron, France