Supplementation of Vitamin D in Patients With Type 2 Diabetes and Hypertension
Not Applicable
Terminated
- Conditions
- Hypertension
- Interventions
- Dietary Supplement: supplementation of 100.000 IU of vitamin D3Dietary Supplement: placebo pill
- Registration Number
- NCT02204527
- Lead Sponsor
- Hospital de Clinicas de Porto Alegre
- Brief Summary
In patients with type 2 diabetes, the effects on blood pressure of vitamin D has been shown to be variable. Thus, the goal of this proposal is to evaluate the effect of vitamin D supplementation in patients with type 2 diabetes and hypertension
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- type 2 diabetes
- hypovitaminosis D
- hypertension
Exclusion Criteria
- pregnant or lactating
- patients using vitamin D supplementation
- using drugs that interfere on vitamin D metabolism (corticosteroids, anticonvulsants)
- illicit drug use
- diseases such as chronic renal failure (serum creatinine greater than 2.0 mg/dl)
- liver cirrhosis
- alcoholism
- dementia
- malignant disease that compromises the 5-year survival,
- digestive tract (malabsorption) diseases
- BMI> 40 kg / m2
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description vitamin D3 supplementation of 100.000 IU of vitamin D3 supplementation of 100.000 IU of vitamin D3 Placebo pill placebo pill Placebo
- Primary Outcome Measures
Name Time Method Ambulatory Blood pressure monitoring up to 24 hours Blood pressure will be assessed by Ambulatory Blood Pressure Monitoring before and after vitamin D supplementation
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
HCPA, Hospital de Clinicas de Porto Alegre
🇧🇷Porto Alegre, Rio Grande do Sul, Brazil