Evaluation of PCO2 and PO2 Values in the Pulmonary Artery and in the Superior Vena Cava: Relationship With Cardiac Output, Hematocrit and Post Operative Organ Dysfunction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Diseases
- Sponsor
- Catholic University of the Sacred Heart
- Enrollment
- 50
- Locations
- 2
- Primary Endpoint
- PCO2 gap changes
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The study is about comparing blood samples obtained from the superior vena cava and the pulmonary artery. The investigators will compare the values of PCO2 and PO2 from these two sites, in order to see if exists a PCO2 gap and a PO2 gap, different from zero. Moreover the investigators want to find out if these gaps are related with changes in the cardiac output, the hematocrit or if they can predict post operative dysfunctions.
Blood samples will be taken at six different times as scheduled by the protocol. Along with the two venous blood samples, an arterial blood sample will be taken too, from a radial of femoral artery catheter.
Investigators
Franco Cavaliere
Professor
Catholic University of the Sacred Heart
Eligibility Criteria
Inclusion Criteria
- •age \> 18 years
- •patient undergoing cardiac surgery with extracorporeal circulation
- •hemodynamic monitoring with a central venous catheter and a Swan Ganz catheter placed in the internal left giugulare vein
Exclusion Criteria
- •severe tricuspid insufficiency
- •EF \< 50%
- •SOFA score \>1 in at least one of all the criteria
Outcomes
Primary Outcomes
PCO2 gap changes
Time Frame: two days
See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery
PO2 gap changes
Time Frame: two days
See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery