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role of ultrasonography and preoperative liver biopsy in diagnosing neonatal jaundice

Not Applicable
Conditions
Health Condition 1: Q442- Atresia of bile ductsHealth Condition 2: null- Neonatal cholestasis
Registration Number
CTRI/2018/05/013552
Lead Sponsor
Santosh Kumar Mahalik
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

All neonates and infants (up to 6 months of age) with jaundice persisting beyond 2 weeks of life will be screened for neonatal cholestasis

Exclusion Criteria

Physiological Jaundice

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Diagnostic accuracy of USG color doppler with liver biopsy in differentiating biliary atresia from other causes of neonatal cholestasisTimepoint: End of the study, 2nd year
Secondary Outcome Measures
NameTimeMethod
1.Accuracy of USG color Doppler (hepatic subcapsular flow) in diagnosis of biliary atresia before 6 weeks <br/ ><br>2.Diagnostic value of various other USG findings in biliary atresia <br/ ><br>3.Safety and efficacy of liver biopsy in comparison to ultrasound in diagnosing biliary atresaTimepoint: 1 year and 2nd year
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