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Clinical Trials/NCT01233700
NCT01233700
Completed
Phase 2

Brief Nursing Intervention to Prevent Poor Psychosocial Outcomes in Living Donors

University of Pittsburgh1 site in 1 country113 target enrollmentMarch 2010
ConditionsLiving Donation

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Living Donation
Sponsor
University of Pittsburgh
Enrollment
113
Locations
1
Primary Endpoint
psychological distress
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the potential effectiveness of a psychosocial intervention based on the principles of motivational interviewing. The novel intervention will assist living donor candidates to think through any remaining concerns or questions that they may have about living donation. If the intervention is effective, it may help to prevent post-donation problems related to psychological and health outcomes.

Detailed Description

The protection of living donors' well-being and the prevention of any negative consequences of donation are among the foremost priorities in transplantation. Some donors experience poor psychosocial outcomes after donation, including psychological distress, poor perceived physical well-being, and strained family relationships. No preventive interventions have been mounted or tested for their ability to avert poor psychosocial outcomes in living donors. The present study will provide an initial test of a new intervention for this purpose. The new intervention utilizes motivational interviewing (MI) to address remaining concerns that individuals may have about proceeding with living donation. Study participants will be randomly assigned to either (a) participate in the MI intervention (during which they will be asked to answer a series of questions to help them better delineate their reasons for and against proceeding with living organ donation), (b) participate in a comparison intervention designed to inform them about healthy lifestyle habits, or (c) not receive any intervention. We plan to recruit a maximum of 150 adults who are considering whether to serve as living kidney or liver donors. We hypothesize that participants receiving the MI intervention will have superior outcomes (less psychological distress, fewer physical health complaints, better interpersonal relationships within their family, better overall quality of life)after donation.

Registry
clinicaltrials.gov
Start Date
March 2010
End Date
April 2013
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mary Amanda Dew

Professor

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • Score of 1 or greater on the Simmons Ambivalence Scale;
  • Must be able to speak English;
  • Have been evaluated as a potential living kidney or liver donor candidate;
  • Aged 18 or older

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

psychological distress

Time Frame: 3 months post-donation

PRIME-MD depression and anxiety modules, BSI anxiety items, Simmons Feelings About Donation items; Simmons Psychosocial Concerns About Donation items

interpersonal relationship quality and distress

Time Frame: 3 months post-donation

Simmons Family Relationship items, Short Dyadic Adjustment Scale, Family ICPS conflict and intimacy subscales

somatic/physical health perceptions

Time Frame: 3 months post-donation

Concerns About Donation Effects items, Simmons Post-donation Medical Concerns, Brief Pain Inventory short form, FACIT-fatigue scale, Post-surgery Body Image Questionnaire, Post-donation Symptom Checklist, Simmons Concerns About Future Health items, Simmons Perceived Stressfulness of Donation items

quality of life

Time Frame: 3 months post-donation

RAND-12

Secondary Outcomes

  • Satisfaction with intervention(pre-donation (on average, 1 week post-intervention but before donation has occurred))
  • Quality of decision to donate(pre-donation (on average, 1 week post-intervention but before donation has occurred))

Study Sites (1)

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