Effects of Pennisetum Purpureum Health Food Supplementation on Muscle Mass and Muscle Strength
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Body height
研究概览
简要总结
The purpose of this study was to investigate the effects of Pennisetum purpureum health food supplementation on muscle mass and muscle strength.
详细描述
All participants performed anthropometric measurements (body height, body weight, BMI, blood pressure, body composition, upper arm circumference, and lower thigh circumference), blood collection (hormones, liver function, and kidney function), exercise test (grip strength and 10-m walking test), as well as questionnaire survey before supplementation. Participants were assigned to either the experimental (n=20) or placebo (n=20) group according to their body composition, upper arm circumference, and lower thigh circumference. The definition of insufficient muscle mass was based on the Asian working group for sarcopenia (AWGS) that skeletal muscle mass in extremities by dual-energy X-ray absorptiometry less than 7.0 kg/m2 in men and less than 5.4 kg/m2 in women is a necessary condition, and one of the following criteria were met: (1) handgrip strength less than 28 kg in men and less than 18 kg in women and (2) 5-time chair stand test over than12 seconds. The anthropometric measurements (body height, body weight, BMI, blood pressure, body composition, upper arm circumference, and lower thigh circumference), blood collection (hormones, liver function, and kidney function), exercise test (grip strength and 10-m walking test), as well as questionnaire survey, were collected after 8 weeks and 12 weeks of supplementation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
A double-blind, matched-pair study design
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult between 18-75 years old
- •skeletal muscle mass in extremities by dual-energy X-ray absorptiometry less than 7.0 kg/m2 in men and less than 5.4 kg/m2 in women
- •one of the following criteria were met: (1) handgrip strength less than 28 kg in men and less than 18 kg in women and (2) 5-time chair stand test over than 12 seconds
排除标准
- •The volunteers have history of cardiovascular, liver, kidney, and diabetes mellitus
- •acute sport injury
- •participated in any clinical trials or experimental research in the last 3 months before our experiment
- •taking supplement during the experimental period
- •did not maintain their regular eating habit or drink alcohol
结局指标
主要结局
Body height
时间窗: 12 weeks of supplementation
Cortisol level
时间窗: 12 weeks of supplementation
Growth Hormone level
时间窗: 12 weeks of supplementation
Insulin-like Growth Factor-1
时间窗: 12 weeks of supplementation
Diastolic blood pressure
时间窗: 12 weeks of supplementation
Body weight
时间窗: 12 weeks of supplementation
ASM (Appendicular Skeletal Muscle Mass)
时间窗: 8 weeks of supplementation
Upper Arm Circumference
时间窗: 12 weeks of supplementation
Testosterone level
时间窗: 12 weeks of supplementation
Thigh Circumference
时间窗: 12 weeks of supplementation
follistain level
时间窗: 12 weeks of supplementation
myostain level
时间窗: 12 weeks of supplementation
BMI (body mass index)
时间窗: 12 weeks of supplementation
Systolic blood pressure
时间窗: 12 weeks of supplementation
Grip Strength
时间窗: 12 weeks of supplementation
10-Meter Walk Test
时间窗: 12 weeks of supplementation
次要结局
未报告次要终点
